Candida parapsilosis is an emerging fungal pathogen that was once thought to be solely a colonizing organism. C. parapsilosis is increasingly becoming reported as the most common Candida species that causes onychomycosis. Clinical findings include typically severe dystrophy of the nail fold and plate as well as thickening and fragmentation of the plate, particularly in the distal plate. We pres...

The present study was to formulate a transungual drug delivery formulation. We targeted to formulate and evaluate fluconazole film for the nail fungal infection using extracted natural and evaluated penetration enhancer (PE). Model drug fluconazole was formulated with the natural extracted penetration enhancer with different ratios. The solvent for PE extraction was methanol and that extracts w...

A 25-year-old construction worker was installing a window from the inside but bent his upper body to the outside through the window. As he used a nail gun to secure parts to the window sill, the nail gun ricocheted and misfired a nail into his left chest. After evaluation at a peripheral hospital, he was quickly transferred to our tertiary care centre. On initial evaluation he was awake and ale...

BACKGROUND Treatment options for nonunion of the femoral shaft fracture after intramedullary nail fixation are controversial. The methods of exchanging an existing nail with a larger-sized nail, dynamization, removal of the nail followed by plating, and bone grafting have all been reported. From those options, exchange nailing seems to be the most popular choice. In our study, we used plate aug...

Beau lines are transverse, band-like depressions extending from one lateral edge of the nail to the other and affecting all nails at corresponding levels (1). Onychomadesis is considered an extreme form of Beau line with subsequent separation of the proximal nail plate from the nail bed. Both fall along a spectrum of nail plate abnormalities that occur secondary to temporary nail matrix arrest ...

This study designs and evaluates a new nail clipper for the elderly using ergonomic methods. The nail clipper usage problems and requirements were collected first. After requirement analysis we applied ergonomic simulation in redesigning the nail clipper and developing a pedal plate. A usability test was conducted to evaluate both typical and newly developed nail clippers using 20 elder partici...

OBJECTIVE To assess glycation of nail proteins as a tool in the diagnosis of diabetes. METHODS Glycation of nail proteins was assessed using a modified photometric nitroblue tetrazolium-based assay, which provides information about average glucose values of the last 6-9 months. Analysis is possible on 10 mg of nail clippings with a within-run coefficient of variation (CV) of 11%. The analyte ...

Peri-implant fractures distal to an antegrade femoral nail are uncommon injuries, with no current consensus on the best treatment modality. We are presenting three cases of periimplant fractures distal to an antegrade femoral nail. All patients sustained an initial traumatic injury, which was managed with an antegrade femoral nail fixation. They subsequently suffer a second injury which causes ...

Weir Mitchell (1872) and Sharpey-Schafer (1931) reported that section of a nerve supplying cutaneous fibres to the fingers results in a retardation of nail growth. Head and Sherren (1905), however, believed that the slowing of growth observed in these cases wvas due entirely to the immobilization of the limb either as a result of splinting or paralysis and that division of sensory fibres withou...