Mycobacterium tuberculosis requires iron for normal growth but faces a limitation of the metal ion due to its low solubility at biological pH and the withholding of iron by the mammalian host. The pathogen expresses the Fe(3+)-specific siderophores mycobactin and carboxymycobactin to chelate the metal ion from insoluble iron and the host proteins transferrin, lactoferrin, and ferritin. Sideroph...

View Online Nano-Micro Conf., 2017, 1, 01009 | 1 Published by Nature Research Society http://nrs.org Broadband terahertz absorber based on sinusoidally-patterned graphene Longfang Ye,* Yao Chen Institute of Electromagnetics and Acoustics, and Department of Electronic Science, Xiamen University, Xiamen 361005, China Corresponding Author. Email: [email protected] Received: 25 May 2017, Accepted: 13...

transfusion in the treatment of thalassemia gives rise to iron deposits in many organs. since there are many obstacles in the use of deferoxamin (dfo) as an iron chelating agent, it is important to find another alternative therapy that can act as iron chelation. the study aims to compare the histopathological pictures of the heart and spleen in iron-induced rats after administration of dfo and ...

The reduction of Triphos [PhP(CH(2)CH(2)PPh(2))(2)] iron halide complexes has been explored, yielding formally zerovalent (κ(3)-Triphos)Fe(κ(2)-Triphos) and (κ(3)-Triphos)Fe(κ(2)-Bpy). Electrochemical analysis, coupled with the metrical parameters of (κ(3)-Triphos)Fe(κ(2)-Bpy), reveal an electronic structure consistent with a π-radical monoanion bipyridine chelate that is antiferromagnetically ...

A new route for the preparation of magneto-responsive polymeric gels involving iron nanoparticles as nano cross-linkers has been described.

D ESFERRIOXAMINE (DF) is currently the most eflective chelator available for the treatment of iron overload in man.’2 Intramuscular injections reduce the rate of iron accumulation and have been shown to arrest the progress of hepatic fibrosis in children with transfusion-dependent thalassemia.3 However, used in this fashion, the drug removes a limited amount of iron, and there has been extensiv...

Regulation of the root high-affinity iron uptake system by whole-plant signals was investigated at the molecular level in Arabidopsis, through monitoring FRO2 and IRT1 gene expression. These two genes encode the root ferric-chelate reductase and the high-affinity iron transporter, respectively, involved in the iron deficiency-induced uptake system. Recovery from iron-deficient conditions and mo...

Iron is an essential element for all living organisms due to its ubiquitous role in redox and other enzymes, especially in the context of respiration and photosynthesis. The iron uptake and storage systems of terrestrial/higher plants are now reasonably well understood, with two basic strategies for iron uptake being distinguished: strategy I plants use a mechanism involving induction of Fe(III...

Equilibrium-dialysis experiments with 59Fe-labelled Fe(III) chelate solutions show that ferritin is capable of binding a limited number of Fe(III) atoms. Some of this Fe(III) is readily removed, but up to about 200 Fe(III) atoms/molecule remain bound after extensive washing. Some exchange of labelled Fe(III) with endogenous unlabelled ferritin Fe occurs during prolonged dialysis against 59Fe(II...