It is well documented that the quality and quantity of prior sleep influence future sleep. For instance, nocturnal sleep restriction leads to an increase in slow wave sleep (SWS) (i.e. SWS rebound) during a subsequent sleep period. However, few studies have examined how prior napping affects daytime sleep architecture. Because daytime naps are recommended for management of disrupted sleep, unde...

T cell migration represents a complex highly coordinated process involving participation of surface receptor/ligand interactions, cytoskeletal rearrangements, and phosphorylation-dependent signaling cascades. Members of the A-kinase anchoring protein (AKAP) family of giant scaffolding proteins can assemble and compartmentalize multiple signaling and structural molecules thereby providing a plat...

BACKGROUND/AIMS Polyethylene glycol (PEG)-based gut lavage solutions are safe and effective, but require the intake of large volumes of fluid. The use of 2 L PEG plus 45 mL sodium phosphate (PEG2 plus NaP) was compared with 4 L PEG (PEG4) for bowel cleansing before colonoscopy. METHODS Patients were randomized to the PEG2 plus NaP group or PEG4 group between January 1, 2009 and March 31, 2010...

This study investigated the effects of a short afternoon nap (<30 min) in the elderly on subjective mood, performance and electroencephalograms (EEG). Ten healthy elderly persons who habitually napped in the afternoon three or more times a week participated in the present study. They participated in two experimental conditions with an interval of more than five days. In the nap condition, the p...

Mutated disrupted in schizophrenia 1 (DISC1), a microtubule regulating protein, leads to schizophrenia and other psychiatric illnesses. It is hypothesized that microtubule stabilization may provide neuroprotection in schizophrenia. The NAP (NAPVSIPQ) sequence of activity-dependent neuroprotective protein (ADNP) contains the SxIP motif, microtubule end binding (EB) protein target, which is criti...

NAP, a detection and recovery based scheme for implementing fault-tolerant itinerant computations, is presented. We give the semantics for the scheme and describe a protocol that implements NAP in tacoma.

OBJECTIVES: To assess the effectiveness and safety of delayed antibiotic prescription (DAP) compared to immediate (IAP) no (NAP) in children with uncomplicated respiratory infections. METHODS: Randomized clinical trial comparing 3 strategies. The participants were acute infections attended 39 primary care centers. Children randomly assigned into arms as follows: (1) DAP, (2) IAP, or (3) NAP. Pr...

We address the problem of transferring bulk data in environmentally-powered wireless sensor networks where duty cycle compliance is critical for their uninterrupted operation. We propose Pump-and-Nap, a packet train forwarding technique that maximizes throughput while simultaneously enforcing compliance to dynamic duty cycle limitations. A node using Pump-and-Nap operates by pumping a train of ...

The peptide drug candidate NAP (davunetide) has demonstrated protective effects in various in vivo and in vitro models of neurodegeneration. NAP was shown to reduce tau hyperphosphorylation as well as to prevent caspase-3 activation and cytochrome-3 release from mitochondria, both characteristic of apoptotic cell death. Recent studies suggest that caspases may play a role in tau pathology. The ...