Abstract Introduction Vitiligo is an autoimmune skin disease represented by melanocytes destruction. Clinically, it evolves with spots that are lighter than normal color. Periodical evaluation of patients recommended, including thyroid function. Phototherapy its gold standard treatment, consisting in specific range ultraviolet B (UVB) light sections. Sleep may play immunological role, and shoul...

BACKGROUND The Dead Sea basin, the lowest terrestrial point on earth, is recognized as a natural treatment center for patients with various cutaneous and rheumatic diseases. Psoriasis is the major skin disease treated at the Dead Sea with excellent improvement to complete clearance exceeding 85% after 4 weeks of treatment. These results were postulated to be associated with a unique spectrum of...

We have observed an increasing number of patients referred to the Scottish Photobiology Service (SPS), who were later diagnosed with actinic folliculitis (AF) and had positive phototesting results. Treatment options for AF are limited, only a few reports in literature. The use prophylactic narrowband ultraviolet B (NB?UVB) phototherapy has not previously been described, we report on this first ...

BACKGROUND Vitiligo is an acquired disease of skin that presents with depigmented patches due to lack of melanocytes in the epidermis. Accumulation of toxic free radicals like hydrogen peroxide in the epidermis may be responsible for melanocytes death. Since ethyl vanillate (vanillic acid ethyl ester) is a strong hydrogen peroxide scavenger, it may be effective against vitiligo. This study was ...

Generalized pruritus is a common symptom in elderly, patients, with severe impact on the quality of life. The diagnosis of senile idiopathic pruritus is made after the exclusion of a systemic disease such as chronic renal disease, hepatobilliary disease with cholestasis, thyroid dysfunctions, drug-induced hypersensitivity reactions, visceral or hematological neoplasia, and primitive dermatologi...

Vitiligo is the most common depigmenting disorder, with a prevalence of approximately 0.5% in the world population. Almost half of the patients with vitiligo present before 20 years of age. The two sexes are affected equally, and there are no apparent differences according to skin type or race.1,2 On histology, vitiligo is identified by the loss of epidermal melanocytes with absence of inflamma...

Mycosis fungoides (MF) is typically an indolent disease except when large cell transformation (LCT) occurs. The incidence of LCT has been reported to range from 6% to 23% under the criterion of the presence of more than 25% of large cells in a biopsy of typical MF lesions. LCT is more common in advanced-stage MF, but very rarely found in its early stage. Herein, we present a 45-year-old womanwi...

Many therapeutic options have been suggested for the treatment of vitiligo including non-surgical and surgical modalities. Non-surgical modalities, considered the first line therapy, include topical, intra-lesional and systemic corticosteroids, topical and oral psoralen plus ultraviolet A (PUVA), topical khellin 3%-4%-5%, broadband and narrow-band UVB (311 nm UVB phototherapy), and recently, to...