5 Correspondence: Roxana Duda 1 Calistrat Grozovici Str., 2 District, Bucharest, Romania e-mail: [email protected] Abstract. Introduction. Chronic rhinosinusitis with nasal polyposis is an important and complex disease characterized by a persistent inflammatory process involving the sinonasal mucosa, representing a serious health problem and economic challenge, with pathogenic mechanisms st...

OBJECTIVES/HYPOTHESIS Although many proinflammatory cytokines have been identified in nasal polyp tissue, the initial trigger that causes this inflammation characterized by edema, lymphocytosis, and eosinophilia, is still unknown. The purpose of the present study is to identify the presence of genetic polymorphisms in proinflammatory, anti-inflammatory, and chemokine genes that might contribute...

Respiratory epithelial adenomatoid hamartoma (REAH) is a rare benign lesion in nasal cavity. We report two cases of REAH of the nasal cavity arising from nasal septum. The etiology of REAH is unknown although inflammation may induce gland proliferation observed in hamartomas. One of our cases was associated with nasal polyposis. REAH is a self-limiting disease, so it is important to differentia...

Introduction Nasal obstruction is one of the main rhinologic complaints, and two diseases must be investigated as differential diagnosis: rhinosinusal polyposis and inverted papilloma. Using traditional methods, the differential diagnosis between these diseases may be difficult. The morphometric study may be a useful tool for differential diagnosis and to define prognosis. Objective Calculate t...

UNLABELLED Nasal polyposis affects about 1 to 4% of the population. Polyps develop in oedematous and inflammated mucous membrane. In spite of the intensive research the pathomechanism of their development is not fully understood. The majority of the theories concerning the development of nasal polyps emphasize the role of the inflammatory process causing the rupture of the epithelium and the ba...

Fungal rhinosinusitis is an increasingly recognized entity in both immunocompromised as well as immunocompetent patients. Aspergillus spp. is commonest of all causative fungi. A case of chronic fungal rhinosinusitis in a16-year-old immunocompetent female is reported. Presenting symptoms were bilateral nasal block, discharge, and change of voice. Initially, it was diagnosed as nasal polyposis. M...

Differential diagnosis of unilateral nasal mass may be a troublesome question, and also unusual conditions such as glandular hamartoma, consisting in non-neoplastic or inborn malformation, must be considered. We here describe a 78-year-old patient with an unilateral nasal mass, associated to a bilateral naso-sinusal polyposis, which was initially considered to be an inverted papilloma, (on the ...