1. Freehouse International Ltd., Gibraltar 2. StopTB, World Health Organization, Geneva, Switzerland 3. Department of Health, KwaZulu-Natal, Pietermaritzburg, South Africa 4. South African Centre for Epidemiological Modelling and Analysis, Stellenbosch, South Africa 5. Medical Research Council, Durban, South Africa 6. Academic Complex Business Unit, Inkosi Albert Luthuli Central Hospital, Natio...

Toward a therapeutic intervention of lissencephaly, we applied a novel calpain inhibitor, SNJ1945. Peri-natal or post-natal treatment with SNJ1945 rescued defective neuronal migration in Lis1⁺/⁻ mice, impaired behavioral performance and improvement of ¹⁸F-FDG uptake. Furthermore, SNJ1945 improved the neural circuit formation and retrograde transport of NFG in Lis1⁺/⁻ mice. Thus, SNJ1945 is a po...

1Department of Chemical Engineering, MIT, Cambridge, MA 02139, USA, 2Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, MA 02129, USA, 3HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, and KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), University of KwaZulu-Natal, Durban 4013, South ...

The tribe Cephenniini is recorded for the first time in the Republic of South Africa. Five new species are described and str.) sodwanaensis sp. n. (all from KwaZulu-Natal Prov.), Cephennomicrus ubomboensis sp. n. (KwaZulu-Natal), Cm. endroedyi sp. n. and Cm. transkeianus sp. n. (from Eastern Cape). A distributional summary of continental Afrotropical Cephennodes and Cephennomicrus species is gi...

Social status in randomly constituted groups of male CFLP mice was predictable from early suckling behaviour and rate of weight gain in natal litters. High-ranking males were those that had suckled on more anterior teats and gained weight more quickly. Rank was not predicted by any measures of sibling interaction or hormone (testosterone, corticosterone) concentration. Aggressiveness in eventua...

Chlorpyrifos is a pesticide, member of the organophosphate class, widely used in several countries to manage insect pests on many agricultural crops. Currently, chlorpyrifos health risks are being reevaluated due to possible adverse effects, especially on the central nervous system. The aim of this study was to investigate the possible action of this pesticide on the behaviors related to anxiet...

AIM The purpose of this systematic review was to identify and review the literature concerning natal and neonatal teeth. STUDY DESIGN AND METHODS The literature search was conducted using several databases. Specific terms were used in the search, which includes articles from 1950 to 2011, supplementary searching by hand was also used. Relevant studies were selected according to predetermined ...

The inferred parameters of the binary black hole GW151226 are consistent with nonzero spin for the most massive black hole, misaligned from the binary's orbital angular momentum. If the black holes formed through isolated binary evolution from an initially aligned binary star, this misalignment would then arise from a natal kick imparted to the first-born black hole at its birth during stellar ...

-The responsiveness of female White-crowned Sparrows (Zonotrichia leucophrys nuttalli) to male songs in their natal dialect (Clear) or in an alien dialect (Buzzy) was evaluated by measuring string-gathering and papershredding in a laboratory experiment. Females hearing Clear dialect songs gathered more strings than did females hearing Buzzy dialect songs. More females hearing Buzzy songs shredd...

F ollowing extraction of a natal or neonatal tooth, continued growth of the dental papilla may occur and a tooth-like form may develop.'^ This report describes an atypical tooth form (probably the result of continued growth of the retained dental papilla) that abscessed and may have caused delayed eruption of the adjacent primary lateral incisor. A 13-month-old white male presented to the autho...