BACKGROUND The aim of the project is to retrospectively study the changes in bacterial pathogens in acute neonatal bacterial conjunctivitis from 2002 to 2016 in Southern China. The results may provide the guidance for drug choice for acute neonatal bacterial conjunctivitis. METHODS Secretion specimens for bacterial culture were taken from 485 cases with clinically diagnosed acute bacterial ne...

We evaluated the Hyplex BloodScreen PCR-enzyme-linked immunosorbent assay (ELISA) system (BAG, Lich, Germany), a new diagnostic test for the direct identification of gram-negative bacilli and gram-positive cocci from positive blood cultures, with 482 positive BACTEC 9240 blood culture bottles. The test involves amplification of the bacterial DNA by multiplex PCR and subsequent hybridization of ...

abstract essential oils (eos) of achillea eriophora, extracted by hydrodistillation and their constituents were analyzed by gas chromatograph (gc) and gc/mass spectrometry using retention indices and fragmentation patterns. the antibacterial effects of the eo was assessed on several food-borne pathogens, namely staphylococcus aureus, bacillus cereus, escherichia coli o157:h7, salmonella enterit...

The evaluation of the activity of the aqueous and ethyl acetate extracts of the leaves of Piper regnellii was tested against gram-positive and gram-negative bacteria. The aqueous extract displayed a weak activity against Staphylococcus aureus and Bacillus subtilis with minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of 1000 micrograms/ml. The ethyl acetate ex...

Toll-like receptor (TLR) family acts as pattern recognition receptors for pathogen-specific molecular patterns. We previously showed that TLR2 recognizes Gram-positive bacterial components whereas TLR4 recognizes LPS, a component of Gram-negative bacteria. MyD88 is shown to be an adaptor molecule essential for TLR family signaling. To investigate the role of TLR family in host defense against G...

background and purpose: the status of medicinal plants in iranian traditional medicine and rich existence of herbal sources, on one hand, and current problems in curing infections, on the other hand, are the factors to study medicinal plants more accurately. tarragon (artemisia dracunculus l.) is a herbaceous plant from asteraceae family, available in planted and farming forms in iran. this stu...

Using the exhaustion-pad-dry-rinse method, chitosan was applied to alkaline-scoured and bleached cotton yarns in a solution with concentrations ranging from 0.2–1% achieve good antimicrobial activity against bacteria Escherichia coli (Gram-negative) Staphylococcus aureus (Gram-positive). Studied samples were also assessed by measuring amount of introduced chitosan, accessible amino groups, mech...

OBJECTIVES Though most bacteria remain susceptible to endogenous antimicrobial peptides, specific resistance mechanisms are known. As mimics of antimicrobial peptides, ceragenins were expected to retain antibacterial activity against Gram-positive and -negative bacteria, even after prolonged exposure. Serial passaging of bacteria to a lead ceragenin, CSA-13, was performed with representative pa...