background: x-linked lissencephaly with ambiguous genitalia (xlag) is a recently described genetic disorder, in which patients present with lissencephaly, agenesis of the corpus callosum, refractory epilepsy of neonatal onset, acquired microcephaly, and male genotype with ambiguous genitalia. xlag is responsible for a severe neurological disorder of neonatal onset in boys. a gyration defect con...

background: postpartum care at home is a post delivery care method that can be provided by public health nurses, trained health workers, or midwifery nurses. a study conducted to compare effect of two midwife visits at home to usual postpartum care on the healthy behaviors of low-risk iranian mothers. methods: a randomized controlled trial conducted on 200 mothers at a reference center for scre...

COVID-19, a clinical syndrome caused by the coronavirus (SARS-CoV-2) became pandemic following an outbreak of viral pneumonitis, first identified in Wuhan, China. The disease manifestations vary ranging from mild upper respiratory tract infection to severe acute distress (ARDS) and even death. Although most neonatal cases are asymptomatic, rarely, they can present with cytokine storm mimicking ...

HELLP syndrome is most often diagnosed between 27 and 37 weeks gestation. It is also a diagnosis that can be seen during the postpartum period. The effects of HELLP syndrome on the neonate can be significant. Recognizing the risks to the neonate can assist the clinician in preparing for the neonate prior to delivery. In doing so, the mortality and morbidity rates can be reduced.

Bacteremic/20 wk PEN × 9 d Uncomplicated term delivery; neonate unaffected Zervoudakis and Cederqvist, 1977 Bacteremic/19 wk AMP × 3 wk Uncomplicated term delivery; neonate unaffected Hume, 1976 Bacteremic/18 wk AMP × 2 wk; then PO AMX Uncomplicated delivery at 39 wk; neonate unaffected Benshushan et al., 2002 Bacteremic/18 wk AMP × 7 d, GEN × 2 d; then PO AMX Diagnosed postpartum; preterm deli...

The immune response of the neonate is poor and is dependent on passive immunity provided by maternal Ig. However, here we show that exposure of the neonate to environmental antigens induces a germinal center (GC) reaction. In the peripheral blood of premature infants one finds IgG class switched B cells expressing a selected V-gene repertoire. These data suggest that restrictions in the reperto...

1. Describe the association between gestational age, birthweight, and postnatal age and blood pressure in the neonate. 2. Delineate the primary clinical consideration in an infant who has hypotension. 3. Describe the controversy surrounding the relationship between antenatal steroid therapy and neonatal blood pressure. 4. Delineate the aspects of management of respiratory illnesses in the neona...

Of the many challenges facing professionals who practice in neonatal intensive care in the United States, the question of what type of facility is optimal has been debated for more than a decade. We have attempted to explore this question at Sanford Children’s Hospital in Sioux Falls, SD. The purpose of this article is to briefly summarize our work and other significant research findings regard...

background: adrenal hematoma is a very rare acquired cause of neonatal hypertension. in this study, we report a case of neonatal hypertension associated with adrenal hematoma. a male neonate was immediately transferred to our neonatal intensive care unit after delivery due to meconium aspiration. he needed to be on mechanical ventilation support. during his hospital stay, hospital records showe...