The findings in iris fluorescein angiograms of 48 eyes with central retinal vein occlusion (CRVO) were correlated with the predominant retinal vascular response. In 24 eyes with the non-ischaemic type of CRVO there were no or only minimal iris vessel changes, whereas in all 24 eyes with ischaemic type of CRVO there was iris vessel dilatation and leakage with or without neovascularisation. These...

Eight eyes with central retinal vein occlusion one eye with old central retinal artery occlusion complicated by rubeosis iridis or increased intraocular pressure, or both; and one eye with diabetic retinopathy and rubeosis iridis were treated by retinal panphotocoagulation. Vision did not improve but intraocular pressure was lower and iris neovascularisation regressed in most cases, supporting ...

RETINAL micro-aneurysms were observed histologically by Mackenzie and Nettleship as early as 1879. However, these observations passed unnoticed until 1943 when Ballantyne and Loewenstein found numerous spherical micro-aneurysms on the capillaries in flat histological sections of retinae from diabetics. These microaneurysms were conceived to be the histological substrate for the small sanguinole...

We present the case of a 13-year-old girl with a right congenital esotropia who at the age of 6 months presented an anomaly of the optic disc and retinal vessels in the same eye. In the following year she developed Coats's disease, rubeosis iridis, and neovascular glaucoma that led to enucleation. Pathological examination confirmed the clinical diagnosis.

This review provides a detailed summary of the issues etiology, pathogenesis and molecular mechanisms corneal neovascularization. Signaling molecules involved in process neovasculogenesis, as well their antagonists, antiangiogenic factors, are described. The role signaling proteins VEGF, MMP receptors modern targets therapy is described on basis series clinical studies. potentials gene bioengin...

The iris vascular bed of eyes with pseudoexfoliation syndrome has been studied with electron microscopy. Two of the eyes suffered from painful glaucoma, whereas the third showed normal intraocular pressure. The following changes were observed: (1) deposits of pseudoexfoliation material lying adjacent to the endothelial wall; (2) thin vessel basement membrane, sometimes even interrupted; (3) ext...

In the Eye Outpatient Department of H.P. Medical College Hospital, Simla, nine cases of capsular exfoliation affecting seventeen eyes were seen in the course of 6 months. Their main features are given in Table I (overleaf, pp. I22 and 123). All the patients were males between the ages of 6o and 76 years. The capsular exfoliation was associated with phakodonesis, iridodonesis, glaucoma, primary ...

A frequently cited theory for the pathogenesis of neovascularization in diabetic retinopathy is that retinal hypoxia and/or ischemia release a factor which stimulates neovascularization. To the authors' knowledge, there is no direct in vivo evidence in the human proving this theory. One hundred and twenty-two diabetic subjects were studied to see whether worsening retinopathy was associated wit...

background: to compare the efficacy of subconjunctival administration of bevacizumab and different doses of sunitinib malate in reducing corneal neovascularization (cnv). materials and methods: in this experimental study, central corneal cauterization was created in the right eye of fifty male sprague–dawley rats. on day 1 (1 week after cauterization), rats were randomly assigned into five trea...