نتایج جستجو برای: nephroprotective activity

تعداد نتایج: 1134807  

2015
Yan-Xi Zhou Wei Xia Wei Yue Cheng Peng Khalid Rahman Hong Zhang

Rhein (4, 5-dihydroxyanthraquinone-2-carboxylic acid) is a lipophilic anthraquinone extensively found in medicinal herbs, such as Rheum palmatum L., Cassia tora L., Polygonum multiflorum Thunb., and Aloe barbadensis Miller, which have been used medicinally in China for more than 1,000 years. Its biological activities related to human health are being explored actively. Emerging evidence suggest...

2015
Suheir Assady Joel Alter Elena Axelman Yaniv Zohar Edmond Sabo Michael Litvak Marielle Kaplan Neta Ilan Israel Vlodavsky Zaid Abassi

BACKGROUND Heparanase, an endoglycosidase that cleaves heparan sulfate (HS), is involved in various biologic processes. Recently, an association between heparanase and glomerular injury was suggested. The present study examines the involvement of heparanase in the pathogenesis of Adriamycin-induced nephrotic syndrome (ADR-NS) in a mouse model. METHODS BALB/c wild-type (wt) mice and heparanase...

Journal: :Vestnik Volgogradskogo gosudarstvennogo medicinskogo universiteta 2022

Resume. The search for new drugs with cytoprotective and anti-ischemic activity is an urgent task of modern pharmacology. These properties are necessary the complex protection renal parenchyma during organ preservation operations (renal resection), most often carried out in conditions thermal ischemia. Only combined use highly effective skill operating surgeon can prevent development acute inju...

Journal: :Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 2020

Journal: :Planta Medica 2021

Abstract Artemisia annua (annual mugwort) is a species that has long been used in traditional Asian medicine, mainly Chinese and Hindu. The widespread known as medicinal plant not only Asia but also Europe, both Americas, Australia. become subject of particular interest due to the 2015 Nobel Prize awarded for detecting sesquiterpene lactone artemisinin it proving its antimalarial activities. ra...

2016
D. K. YADAV

The present study was conducted to evaluate the effect of alcoholic extract A.webbiana leaves Lindl on liver and kidney. Wistar rats were divided into three groups (n=3) for hepatotoxicity and nephrotoxicity. Alcoholic leaves extract of A.webbiana was evaluated for protective effects against CCl4 induced hepatotoxicity and cisplatin induced nephrotoxicity. Hepatotoxicity studied by comparing pa...

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