Abstract Diabetes mellitus (DM) is a metabolic disease with an increasing prevalence. An increase in free radicals and AGEs can cause glomerular cell damage which lead to inflammation DM nephropathy. WHO has recommended treatment by using herbal medicines that have minimal side effects lot of biological activity prevent complications. Coprinus comatus (O.F. Mull.) known as immunomodulatory, ant...

BACKGROUND Most chemotherapeutic drugs are known to cause nephrotoxicity. Therefore, new strategies have been considered to prevent chemotherapy-induced nephrotoxicity. It is of note that Nigella sativa (NS), or its isolated compound Thymoquinone (TQ), has a potential role in combating chemotherapy-induced nephrotoxicity. AIM To analyze and report the outcome of experimental animal studies on...

Article history: Received on: 26/10/2016 Accepted on: 30/12/2016 Available online: 30/05/2017 The protective effect of wheat germ oil (WGO) as a natural antioxidant was evaluated against carbon tetrachloride (CCl4)-induced nephrotoxicity, genotoxicity and alterations in gene expression in mice kidney. WGO group: received olive oil orally for 2 days then WGO orally for 8 days, CCl4 group: receiv...

Background: Cisplatin is an effective chemotherapy but its main side effect, acute kidney injury, limits use. Panduratin A, a bioactive compound extracted from Boesenbergia rotunda, shows several biological activities such as anti-oxidative effects. The present study investigated the nephroprotective effect of panduratin A on cisplatin-induced renal injury. Methods: We toxicity cisplatin in bot...

Objective- To evaluate and compare kidney function with and without saffron administration and consider the diuretic and nephroprotective effects of aqueous extract of this substance in normal cats. Design- Descriptive study Animals- 6 female healthy cats (age: 2 to 4 years, average weight: 4 kg) - no clinical sign of renal disorders and prior to presentation Procedures- The scintigraphy of r...

Physalis peruviana (physalis) has long held a place in folk medicine in the tropical countries where it grows. Here, the aim of this study was to evaluate the potential nephroprotective impact of physalis extract against carbon tetrachloride (CCl4)-induced kidney injury and to explore the possible mechanisms by which this plant exerts its beneficial effects. Rats were randomly divided into equa...

Objective: Plants have been used to treat ailments since the dawn of humanity. The use medicinal plants for various purposes such as preventing diseases, treating diseases and supporting medical treatment is increasing day by day. On other hand, are important sources raw materials pharmaceutical industry. It has demonstrated that Peganum harmala L. phytochemicals it contains a wide variety phar...