Within the African context, shortages of medical personnel, funding and facilities make it imperative that these scarce resources are utilised optimally. Screening for diabetic retinopathy has been performed by several different kinds of health care personnel, including general practitioners and optometrists, and dilated mydriatic colour fundus photography is currently regarded as the most effe...

OBJECTIVE To evaluate the molecular genetic defects associated with retinitis punctata albescens (RPA) in 5 patients from 3 families with this disease. METHODS We examined 3 probands and 2 clinically affected relatives with RPA. Clinical examinations included best-corrected visual acuity, visual field testing, electroretinography, dilated fundus examination, and fundus photography. Leukocyte ...

Ancillary investigations are the backbone of uveitis workup for posterior segment inflammations. They help in establishing the differential diagnosis and making certain diagnosis by ruling out certain pathologies and are a useful aid in monitoring response to therapy during follow-up. These investigations include fundus photography including ultra wide field angiography, fundus autofluorescence...

OBJECTIVE To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older. DESIGN Random sample, cross sectional. MATERIALS AND METHODS Response rate was 75.8%. The presence and severity of various characteristics of drusen and pigmentary changes that are typical of ARM...

PURPOSE To study different aspects of macular function in eyes with early age-related macular degeneration (early AMD: drusen with or without retinal pigment epithelium alterations) and normal visual acuity, to obtain a complete evaluation of macular function impairment in early AMD and to study the relationship between macular function and the ophthalmoscopic signs of early AMD. METHODS Fort...

Age-related macular degeneration (AMD) and related macular dystrophies (MDs) are a major cause of vision loss. However, the mechanisms underlying their progression remain ill-defined. This is partly due to the lack of disease models recapitulating the human pathology. Furthermore, in vivo studies have yielded limited understanding of the role of specific cell types in the eye vs. systemic influ...

The method of stereoscopic fundus photography, where both photographs are taken simultaneously, yields the most consistent and reproducible record of depths in the fundus. However, all systems devised to date have had undesirable photographic aberrations. For the most part, this has resulted because the optical axis of each image is not the same as that of the objective lens. A single-axis syst...

PURPOSE To describe clinical and imaging findings in two eyes with new onset subtle neovascular age-related macular degeneration that was detected by the regular use of a home monitoring device based on preferential hyperacuity visual field testing. METHODS Interventional case report. RESULTS Case 1, an 82-year-old man with the intermediate stage of age-related macular degeneration in both ...

Methods: Demographic, lifestyle, and medical characteristics were ascertained on 4519 AREDS participants aged 60 to 80 years at enrollment. Stereoscopic color fundus photographs were used to categorize participants into 4 AMD severity groups and a control group (participants with 15 small drusen). Nutrient intake was estimated from a self-administered semiquantitative food frequency questionnai...