Extrapulmonary manifestations of Mycoplasma pneumoniae pneumonia are uncommon and include hematologic, gastrointestinal, musculoskeletal, dermatologic, and neurologic complications. We report a case of serologically-confirmed M. pneumoniae infection complicated by severe neutropenia, thrombocytopenia, and hepatitis. The presence of antiplatelet and antineutrophil antibodies suggested that these...

Neuropsychiatric manifestations of systemic lupus erythematosus are varied. Presently nineteen in number, they are classified as whether affecting the central or the peripheral compartments of the nervous system. Its diagnosis however remains difficult, more so when two or more of the syndromes are found concomitantly in the same patient and when they occur in absence of the more classical rash...

Introduction Human Parvovirus B19 (HPVB19) is the responsible agent of fifth disease. Other less common manifestations include transient aplastic crisis, nonimmune hydropsfetalis, chronic arthritis, myocarditis, hepatitis, multisystemic vasculitis, renal disease, and idiopathic thrombocytopenic purpura. An increasing number of reports have described HPVB19 infection in association with a variet...

Hepatitis C virus infection is an emerging disease and a public health problem in the world. There are accumulating data regarding extra hepatic manifestation of HCV, such as rheumatologic manifestations, endocrine, hematologic, dermatologic, renal, neurologic, and systemic manifestations. The therapy of them needs more attention to some exacerbations of extra hepatic manifestation and in some ...

PURPOSE OF REVIEW Neurologic complications of human immunodeficiency virus (HIV) infection remain common, despite effective antiretroviral treatment (ART). Neurologic manifestations may be due to opportunistic infection, immune reconstitution, or the virus itself, posing diagnostic challenges for the neurologist. Neurologists are also asked to comment on the use of immunomodulatory agents in th...

For the growing number of patients suffering from post-COVID-19 syndrome, there is little definitive guidance for treatment protocols or prognosis. Neurologic manifestations following acute COVID-19 infection are continually surfacing in literature, with fatigue being most common persistent symptom. This case study follows a 44-year-old female experiencing debilitating and neurologic symptoms p...

The authors report clinical features of ocular manifestations in patients with multiple sclerosis (MS), those that affect the visual sensory system and those that affect the ocular motor system. Disturbances of visual sensory function may precede, manifest coincidentally or follow the neurologic manifestations. Visual disturbances are common in MS and often a result of acute demyelinating optic...

Abstract Background During the current pandemic, there is an increased incidence of neurologic/neuropsychiatric manifestations in patients with novel coronavirus (COVID-19). Neurologic may be coincident or result disease and its therapy. In emergency department, orientation clinician this issue crucial for accurate decision making to limit spread infection during neurologic treatment. This stud...

Mitochondria play essential role in eukaryotic cells including in the oxidative phosphorylation and generation of adenosine triphosphate via the electron-transport chain. Therefore, defects in mitochondrial DNA (mtDNA) can result in mitochondrial dysfunction which leads to various mitochondrial disorders that may present with various neurologic and non-neurologic manifestations. Mutations in th...

The authors report the case of a patient presenting with cutaneous, renal and neurologic vasculitis in the course of relapsing polychondritis (RPC). A 78-year-old man presented with a palpable purpura of the lower limbs, high fever arthralgias, delirium, and nephrotic syndrome. He had a history of relapsing polychondritis treated by corticosteroids. Renal biopsy showed diffuse endo- and extraca...