the short and long term effects of chromium toxicity on brain catecholamines and acetylcholinesterase levels were investigated. rats were injected daily with varying amounts of chromium. the short term (2 h) administration of chromium (8 mmol/kg) reduced catecholamines level of cerebellum, mid-brain and brain-cortex by 22.8, 19.4 and 21.2% respectively. acetylcholinesterase activity was also re...

tuberculous meningitis (tbm) and acute bacterial meningitis (abm) cause substantial mortality and morbidity in both children and adults. identification of poor prognostic factors at patient's admission could prepare physicians for more aggressive monitoring of patients with meningitis. the objective of this study was to determine the predictive value of neurological features to differentiate ab...

many studies concerning persian history have been performed. persian physicians and scientists greatly contributed to medical sciences by their own observations, experimentations and skills through more than seven thousand years of persian history. in persian medieval medicine, different fields were described. among these fields, neurological disorders, especially headache and epilepsy were exp...

Intraventricular meningiomas require a cautious surgical preoperative planning in an attempt to avoid unwanted postoperative neurological déficits. Despite that better approaches exist, the posterior parietal transcortical approach intraventricular trigonal lesions, with its unavoidable damage white matter pathways, is still popular clinical practice, at times,like following case report, withou...

INTRODUCTION The aim of this study was to evaluate the Amiel-Tison neurological examination (AT) and cranial ultrasound at term for predicting the neurological result at 12 months in newborns with neurological risk. PATIENTS AND METHODS The study included 89 newborns with high risk of neurological damage, who were discharged from the Neonatal Intensive Care of the Hospital Zonal Bariloche, Ar...

Free radicals are produced in cells by cellular metabolism and by exogenous agents. These species react with biomolecules in cells and one of the important targets is DNA. This kind of damage, often referred to as oxidative DNA damage, has consequences in various organs and particularly in brain, in view of its high metabolic activity and oxygen consumption. The consequences include mutagenesis...

Hypoxic-ischemic injuries (HII) of the brain, optic pathways, and skin are frequently associated with poor neurological and clinical outcome. Unfortunately, no new therapeutic approaches have been proposed for these conditions. Recently, experimental and clinical studies showed that nerve growth factor (NGF) can improve neurological deficits, visual loss and skin damage after HII. Based on thes...

Infection by Shiga toxin-producing Escherichia coli causes hemorrhagic colitis, hemolytic uremic syndrome (HUS), acute renal failure, and also central nervous system complications in around 30% of the children affected. Besides, neurological deficits are one of the most unrepairable and untreatable outcomes of HUS. Study of the striatum is relevant because basal ganglia are one of the brain are...

Brief episodes of hypotension have been shown to cause acute brain damage in animal models. We used a rat hemorrhagic shock model to assess functional outcome and to measure the relative neuronal damage at 1, 4 and 14 days post-injury (3 min of hypotension). All rats underwent a neurological assessment including motor abilities, sensory system evaluation and retrograde memory at post-hypotensiv...

background: early warning of potential damage to spinal cord during major spinal surgery is highly desirable to prevent post-operative neurological deficits. wake-up test is a simple, safe and reliable method of recognition of such a complication, and has been extensively used in many spinal surgical units. the present study is evaluating the remifentanil, propofol versus alfentanil, propofol a...