Genetically modified animal models are commonly used for in vivo studies of human diseases. Mice the most common biomedical research, which have provided important insights into disease pathogenesis and widely to find treatments However, due differences anatomical structure physiological function between mouse brains, genetically cannot fully recapitulate overt selective neuronal loss seen age-...

Breathing is controlled by complex interactions between the central and peripheral nervous systems in conjunction with respiratory system. Neurological diseases predispose patients to nocturnal desaturation pneumonia due dysfunction, which increases mortality, daytime sleepiness fatigue, reduces quality of life. Respiratory function tests are required identify decline consider compensatory mana...

Background & Objective: Regarding the significance of neurological diseases, training general practitioners has a key role and they should be well-trained in diagnose and approaching different diseases in this field. We focused on educational needs assessment for general practitioners in the field of neurological diseases. Methods: All the general practitioners practicing in the regulatory z...

The pathogenesis of neurological diseases and disorders remains mostly unknown. Neuroinflammation has been proposed as a causative factor for neurological diseases. The confirmation that neurogenesis occurs in the adult brain and neural stem cells (NSCs) reside in the adult central nervous system (CNS) of mammals has tremendous implications for our understanding of the physio- and pathology of ...

BACKGROUND Plasma HIV RNA levels reflect systemic viral replication but in CNS it may occur relatively independent of systemic infection, yet clinical application of CSF HIV-1 RNA levels is less clear. OBJECTIVE To compare CSF and plasma HIV-1 RNA levels of patients with different opportunistic neurological diseases to those without neurological disease, as well as to correlate these levels w...