نتایج جستجو برای: neuromedin u

تعداد نتایج: 165285  

Journal: :IUPHAR/BPS guide to pharmacology CITE 2023

Neurotensin receptors (nomenclature as recommended by NC-IUPHAR [39]) are activated the endogenous tridecapeptide neurotensin (pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu) derived from a precursor (NTS, 30990), which also generates neuromedin N, an agonist at NTS2 receptor. [3H]neurotensin (human, mouse, rat) and [125I]neurotensin may be used to label NTS1 0.1-0.3 3-5 nM concentrations...

2012
Selim Terhzaz Pablo Cabrero Joris H. Robben Jonathan C. Radford Brian D. Hudson Graeme Milligan Julian A. T. Dow Shireen-A. Davies

The capa peptide receptor, capaR (CG14575), is a G-protein coupled receptor (GPCR) for the D. melanogaster capa neuropeptides, Drm-capa-1 and -2 (capa-1 and -2). To date, the capa peptide family constitutes the only known nitridergic peptides in insects, so the mechanisms and physiological function of ligand-receptor signalling of this peptide family are of interest. Capa peptide induces calciu...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2006
Andrea S Randi Claudia Cocca Verónica Carbone Mariel Nuñez Máximo Croci Alicia Gutiérrez Rosa Bergoc Diana L Kleiman de Pisarev

Hexachlorobenzene (HCB) is a widespread environmental pollutant. Controversy still exists about the breast carcinogenic properties of organochlorines in humans. The ligands, receptors, and related signaling proteins of the insulin growth factor family are involved in the regulation of breast-cancer cell growth. The aims of this study were to determine: (1) whether HCB is co-carcinogenic in a me...

Journal: :American journal of physiology. Endocrinology and metabolism 2005
Preeti H Jethwa Caroline J Small Kirsty L Smith Asha Seth Sarah J Darch Caroline R Abbott Kevin G Murphy Jeannie F Todd Mohammad A Ghatei Stephen R Bloom

Intracerebroventricular (ICV) administration of Neuromedin U (NMU), a hypothalamic neuropeptide, or leptin, an adipostat hormone released from adipose tissue, reduces food intake and increases energy expenditure. Leptin stimulates the release of NMU in vitro, and NMU expression is reduced in models of low or absent leptin. We investigated the role of NMU in mediating leptin-induced satiety. ICV...

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