Abstract Gangliogliomas are glioneuronal brain tumors that typically present in childhood or early adulthood. Though most often low-grade, new insights needed to refine tumor classification and identify therapeutic approaches, particularly for unresectable, high-grade, and/or recurrent disease. possess a rare population of immature astrocyte-appearing CD34+ cells. CD34 is expressed neuroectoder...

background: in recent years, adipose tissue, due to the stem cells contained within, has found a new special place in laboratory and clinical applications. these adipose‑derived stem cells (adscs) have the same characteristics of bone marrow mesenchymal stem cells (bmscs). although bone marrow (bm) is not easily accessible and its procurements may be painful, most patients possess excess fat wh...

Astrocytes are promising source cells to replace neurons lost disease owing a shared lineage and capacities for dedifferentiation proliferation under pathological conditions. Reprogramming of astrocytes has been achieved by transcription factor modulation, but reprogramming in vitro or vivo using small‐molecule drugs may have several advantages clinical application. For instance, small molecule...