Purpose Biomarkers for several eye and brain diseases are reviewed, where retinal oximetry may help confirm diagnosis or measure severity of disease. These include diabetic retinopathy, central retinal vein occlusion (CRVO), retinitis pigmentosa, glaucoma, and Alzheimer's disease. Methods Retinal oximetry is based on spectrophotometric fundus imaging and measures oxygen saturation in retinal ...

INTRODUCTION Obstructive sleep apnea syndrome (OSAS) is the most serious consequence of adenotonsillar hypertrophy (ATH). The gold standard diagnostic method is polysomnography (PSG) with nocturnal oximetry, but it requires expensive equipment, the presence of a technician and a specialized doctor, and is very time consuming, making the procedure difficult. The recording of pulse oximetry monit...

BACKGROUND Sleep-disordered breathing is a common and serious feature of many paediatric conditions and is particularly a problem in children with Down syndrome. Overnight pulse oximetry is recommended as an initial screening test, but it is unclear how overnight oximetry results should be interpreted and how many nights should be recorded. METHODS This retrospective observational study evalu...

In Duchenne muscular dystrophy (DMD) nocturnal oxygen desaturation occurs during rapid eye movement (REM) sleep. Polysomnography, which requires hospital admission, will detect sleep-related breathing abnormalities. In order to avoid the inconvenience of hospital admission for the disabled patient, we investigated overnight oxygenation in ten boys with DMD by domiciliary oximetry. In four boys ...

measurements under these conditions, Jobes and Nicolson ~ modified an oximetry probe for attachment to the tongue. Gunter 2 found this technique difficult to use since the modified probe kept slipping off. He adapted a peripheral oximetry probe with a metal strip and placed it across the patient's cheek and noted improved reliability of these "buccal" measurements compared with peripheral ones....

INTRODUCTION AND OBJECTIVES Oxygen saturation by pulse oximetry is commonly used for monitoring critical patients, but its utility as a diagnostic marker of acute heart failure has not been assessed. This study analyzed the diagnostic role of oxygen saturation by pulse oximetry in a series of patients with acute myocardial infarction. METHODS In a prospective observational cohort study of 220...

This paper reviews the evidence regarding whether a standardised examination in the newborn period can improve infant health. The review considers aspects of delivering such a service from timing and number of examinations through to who should perform examinations, and whether evidence supports current practice. Infants at higher risk of anomaly such as those born preterm are highlighted. Aspe...