We measured thoracic duct lymph flow rate versus outflow pressure in 7 chronically catheterized adult sheep and in 6 newborn lambs and compared our results to data previously obtained from 10 fetal sheep. In fetal sheep the thoracic duct lymph flow rate was 34.5 +/- 17.2 ml/hr or 11.7 +/- 6.0 ml/kg/hr. Fetal thoracic duct lymph flow deviated from baseline between 8 and 12 torr outflow pressure ...

In humans and experimental animals, structural and functional changes in neural circuits can accompany the development of epilepsy. In the dentate gyrus, seizures enhance adult neurogenesis, but it is unclear to what extent newborn granule cells participate in seizure-induced synaptic reorganization. During the first weeks of their existence, mouse newborn granule cells labeled with enhanced gr...

Cyclic nucleotides are relaxants of the airway smooth muscle, yet most of the available data were obtained in adult animals. The expression and activity of cyclases have been reported to be developmentally regulated in the lung, and little is known about the age-related changes in their bronchial muscle relaxation potential. We evaluated and compared the newborn and adult rat bronchial smooth m...

OBJECTIVE To describe the morphometric and ultra-structural features of the kidney in fetal (20-day-old), newborn (7-day-old) and adult (180-day-old) rats. MATERIALS AND METHODS Kidneys from all animals were excised, fixed in 3% glutaraldehyde in 0.1 M phosphate buffer, post-fixed in 1% phosphate-buffered osmium tetroxide, and examined by stereological and light and electron microscopic metho...

In humans and experimental animals, structural and functional changes in neural circuits can accompany the development of epilepsy. In the dentate gyrus, seizures enhance adult neurogenesis, but it is unclear to what extent newborn granule cells participate in seizureinduced synaptic reorganization. During the first weeks of their existence, mouse newborn granule cells labeled with enhanced gre...

The aim of this study was to investigate the influence of the natural mineral adsorber clinoptilolite on the serum levels of insulin and insulinlike growth factor-I in newborn piglets in the first 30 hours postnatally. A total number of 40 crossbred Landrace x Duroc newborn piglets from 4 litters was used. Five piglets from each litter were randomly assigned to the treated group and another fiv...

The permeability of the alveolar-capillary membrane of newborn and adult mice to horseradish peroxidase (HRP) and catalase was studied by means of ultrastructural cytochemistry, and the permeability to ferritin was studied by electron microscopy. The influence of varying volumes of intravenously injected fluid on the rate of leakage of the tracers from pulmonary capillaries was examined. The tr...

a correlational study was conducted to investigate the relationship between me duration of labor stages and the   newborn 's apgar score in women admitted to imam khomeini hospital (sari 1994).   a total of 1 20 primigravida women admitted for delivery wert' selected sequentially. the tool was a checklist   consisting of three parts . the first part inquired as to certain demographic ...

megacystis microcolon intestinal hypoperistalsis syndrome (mmihs) is a rare and the most severe form of functional intestinal obstruction in the newborn. the characteristic features of this congenital and fatal disease are abdominal distension, absent or decreased bowel peristalsis. abdominal distension is a consequence of the distended, unobstructed urinary bladder with or without hydronephros...

Leptin is an adipocyte-derived peptide hormone regulating energy balance in experimental animals. Although the physiological function of leptin in humans is still unclear, its secretion is closely related to fat mass in adult humans. To examine how fetal growth correlates with leptin levels at birth, an umbilical cord venous blood sample was obtained at the delivery from 50 term newborn infants...