نتایج جستجو برای: nf κb1

تعداد نتایج: 47072  

Journal: :The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2013
Weifeng Shi Xueling Hou Xiang Li Hongjun Peng Mei Shi Qingbo Jiang Xiping Liu Yun Ji Yuhua Yao Caizhen He Xiangdong Lei

BACKGROUND Mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in response to viral infection. The aim of this study was to explore the function and mechanism of MAPK signaling pathway in enterovirus 71 (EV71) infection of human rhabdomyosarcoma (RD) cells. METHODS Apoptosis of RD cells was observed using annexin V-FITC/PI binding assay under a fluorescence micro...

2016
Qian Du Yong Huang Tongtong Wang Xiujuan Zhang Yu Chen Beibei Cui Delong Li Xiaomin Zhao Wenlong Zhang Lingling Chang Dewen Tong

Porcine circovirus type 2 (PCV2) infection caused PCV2-associated diseases (PCVAD) is one of the major emerging immunosuppression diseases in pig industry. In this study, we investigated how PCV2 inoculation increases interleukin (IL)-10 expression in porcine alveolar macrophages (PAMs). PCV2 inoculation significantly upregulated IL-10 expression compared with PCV1. Upon initial PCV2 inoculatio...

2016
Yanni Jiang Hong Wang Hongsong Yu Lin Li Dengfeng Xu Shengping Hou Aize Kijlstra Peizeng Yang

Several modulatory factors in the TLR signaling pathway including IRF3, IRF7, IRF8, TRIM20, MYD88 and NF-κB1 have been associated with autoimmune disease. In this study, we investigated the association of 13 SNPs for these genes with Behçet's disease (BD) and Vogt-Koyanagi-Harada (VKH) syndrome using a polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) assay. Haplotyp...

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