It is possible to cause G2 arrest in Aspergillus nidulans by inactivating either p34cdc2 or NIMA. We therefore investigated the negative control of these two mitosis-promoting kinases after DNA damage. DNA damage caused rapid Tyr15 phosphorylation of p34cdc2 and transient cell cycle arrest but had little effect on the activity of NIMA. Dividing cells deficient in Tyr15 phosphorylation of p34cdc...

Proponemos abordar las figuraciones de la mujer en obra Mario Levrero. A partir del análisis trilogía involuntaria –La ciudad (1970), El lugar (1981) y París (1979)– diálogo con otros textos, destacamos que los personajes femeninos se construyen como monstruos bifrontes: al mismo tiempo impulsan búsqueda reconstructiva protagonista relatos, son un obstáculo para dicha realización. So...

OBJECTIVES The aim of this study was to investigate the constitution of nim gene types, their activating insertion sequence (IS) element, their localization (plasmid or chromosome) and cfiA gene status in metronidazole-resistant Bacteroides strains (n=26) in order to examine their interchangeability. METHODS Southern hybridization and conjugative plasmid transfer were used to localize the nim...

Thiamine stimulates the production of a red pigment, which is chromatographically and spectrophotometrically identical to prodigiosin, by growing cultures of Serratia marcescens mutant 9-3-3. This mutant is blocked in the formation of 2-methyl-3-amylpyrrole (MAP), the monopyrrole moiety of prodigiosin, but accumulates 4-methoxy-2,2,'-bipyrrole-5-carboxaldehyde (MBC) and can couple this compound...