BACKGROUND Multiplicity of infection (MOI) refers to the average number of distinct parasite genotypes concurrently infecting a patient. Although several studies have reported on MOI and the frequency of multiclonal infections in Plasmodium falciparum, there is limited data on Plasmodium vivax. Here, MOI and the frequency of multiclonal infections were studied in areas from South America where ...

Malaria is a protozoan disease caused by the bite of a female anopheline mosquito which is infected by the protozoa Plasmodium. It is the world’s third-ranked infectious killer disease after HIV/AIDS and tuberculosis1. Currently, six species of Plasmodium (P. falciparum, P. vivax, two sympatric species of P. ovale, P. malariae, and P. knowlesi) are known to cause malaria2. Of these, P. vivax wa...

Despite rigorous effort made to control malaria for more than a century, it is still among the main public health problems in least developed regions of the world. Majority of deaths associated with malaria occur in sub-Sahara Africa among biologically risked groups. Thus, this study was designed to assess the incidence of severe malaria syndromes among children in Pawe Hospital, Northwest Ethi...

CONTEXT Today, India faces increasing morbidity and mortality due to malaria, which is a global health burden. Plasmodium vivax which was once considered to have a benign course, is now being increasingly associated with complicated malaria. Studies which have been done on the increasing virulence of P. Vivax in children, are exceptionally rare. AIMS This study has addressed some of the hithe...

Malaria, which is a major infectious disease worldwide, is caused by the Plasmodium parasite, one of the longest-known parasites infecting humans. The malaria situation is complicated by the emergence of drug resistance and the lack of an effective vaccine. Genetic factors play a key role in disease susceptibility, progression and outcome. Interestingly, an increasing large number of polymorphi...

BACKGROUND & OBJECTIVES The proportion of malaria cases that are complicated and fatal are not well described in India. Alipurduar sub-division of Jalpaiguri district in West Bengal is highly endemic for malaria. We constructed a retrospective cohort of severe malaria patients admitted in the secondary and tertiary care facilities in Alipurduar to determine the incidence, assess the management,...

Introduction: Malaria has been a major public health problem plaguing India for centuries and about 95% of Indian population is residing in malaria endemic regions. The proportion of the Pf % has gradually increased from 39% in 1995 to 65% in 2014. Periodic clinical profiling studies may help us in understanding of the changing pattern of the disease, complication rate and emerging drug resista...

The Orissa state on the east coast of India is endemic for malaria for decades1. The state with a population of 3.6%, contributes about 22% of all malaria cases, 43% of the Plasmodium falciparum cases and 33% of total malaria related deaths in the country. Out of 30 districts in Orissa 27 are endemic for malaria and the average annual parasite incidence (API) for the state is 18.6 (+ 13.7). The...

The 2014 malaria epidemiological data reported through the annual malaria statistics reporting system were collected and analyzed. A total of 3 078 malaria cases were reported in 680 counties of 30 Provinces/ Municipalities/Autonomous Regions (P/M/A)(except Inner Mongolia) in 2014, decreased by 25.4% compared with the 4 128 cases in 2013. The incidence rate was 0.022 6/10 000. More cases distri...