BACKGROUND Hodgkin lymphoma is a hematologic malignancy usually confined to lymphatic structures and commonly associated with constitutional symptoms. Bony involvement and musculoskeletal symptoms are uncommon and typically seen in advanced disease. In this case, we report an unusual presentation of classical Hodgkin lymphoma and highlight diagnostic challenges leading to the misdiagnosis and t...

OBJECTIVE To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients. DESIGN Case report. PARTICIPANTS Two patients with yellow creamy infiltrates in fundo. INTERVENTION Both patients had a complete ophthalmologic evaluation and histology was obtained after enucleation of the affected eye. MAIN OUTCOME MEASURES Histology findings of the en...

Histologic transformation (HT) refers to a biologic event leading to the development of a high-grade, aggressive non-Hodgkin lymphoma in patientswith anunderlying follicular lymphoma (FL). Transformation to diffuse large B-cell lymphoma (DLBCL) or Burkitt lymphoma is also known to take place in other subtypes of indolent lymphoma such as marginal zone lymphoma, lymphoplasmacytic lymphoma, small...

OBJECTIVES Non-Hodgkin lymphomas are malignant neoplastic proliferations of the immune system that can manifest as nodal or extranodal lymphomas. The aim of this study was to retrospectively investigate the site of occurrence of lymphomas in the head and neck area and to analyze the typical symptoms of patients who presented at an oral and maxillofacial surgical department. MATERIAL AND METHO...

marginal zone lymphoma (mzl) accounts for between 5% and 17% of all non-hodgkin lymphomas (nhl). w e reported a rare case of marginal zone lymphoma presenting with bilateral ear erythema and swelling. the case was a 79-year-old man who suffered from progressive bilateral ear erythema and swelling since 2 years ago. physical examination was remarkable for erythmatous, edematous and non-tender au...

Provisional hypomyopathic juvenile dermatomyositis is a subgroup of clinically amyopathic juvenile dermatomyositis provisional. The diagnostic criteria include: Classic dermatomyositis skin lesions – which have to be confirmed by biopsy –, no involvement of proximal muscles, subclinical involvement of these muscles and normal level of muscle enzymes. These criteria should be present for a minim...

Burkitt lymphoma (BL) is the most frequent non-Hodgkin lymphoma in pediatric patients, accounting for approximately 34% of the cases of lymphoma in children. This subtype of non-Hodgkin lymphoma was first described in 1958 as a monoclonal proliferation of B cell lymphocytes. Cardiac involvement of BL in association with osseous compromise and lymphadenopathy is rare and poorly documented. We re...

At the time of writing, five anti-CD19 CAR T-cell products are approved by U.S. Food and Drug Administration for seven different indications in lymphoid malignancies, including B-cell non-Hodgkin lymphoma, pediatric acute lymphoblastic leukemia, multiple myeloma. T cells chronic lymphocytic myeloid less common malignancies such as lymphomas Hodgkin lymphoma being tested early-phase clinical tri...

Diffuse large B cell lymphoma (DLBCL) is a frequent aggressive subtype of non-Hodgkin lymphoma, representing nearly 30-40% all cases. The skin may be affected by the disease either primarily or secondarily. Herein we report clinical and dermoscopic case metastasis DLBCL in patient with Klinefelter Syndrome.