• Vol 8 • December 2006 838 Diabetic mastopathy is an uncommon benign histopathologic condition manifested by a palpable mass. It typically occurs in premenopausal women with longstanding early-onset insulin-dependent diabetes mellitus and microvascular complications. It was first reported in 1984 by Soler and Khardori [1] in a series of 12 patients. Since then, over 200 cases have been describ...

Childhood Hodgkins Disease (HD) is a lymphoma that displays characteristic epidemiological, clinical and pathological features according to various geographic areas, particularly according to the socio-economic level of a given country. India presents a similar sex, age and subtype distribution as other emerging countries: high male-to-female ratio, younger age at presentation, high proportion ...

background and objectives: human herpes 6 virus (hhv-6) could remain latent and chronic in the host cells after primary infection. hhv-6 genome encodes certain trans activation proteins which may results in development of malignantlymphoma. the association of human herpes six virus (hhv-6) infection and hodgkin and non-hodgkin lymphomas is strongly supported by epidemiological studies. the aim ...

background epstein-barr virus (ebv) is a dna virus which belongs to the herpesviridae family and in γ-herpesvirus subfamily, has been infected about 95% of the world’s population. ebv is transmitted through saliva and associated with different disease such as infectious mononucleosis, nasopharyngeal carcinoma, burkitt`s lymphoma, hodgkin and non-hodgkin`s lymphoma. the study proposed to determi...

Despite recent advances, there remains a need to improve treatment options and survival outcomes for patients with hematological malignancies. Considerable research is ongoing develop advanced therapy medicinal products (ATMPs) in this disease area. Some ATMPs have already received regulatory apprvoal the number of therapeutic range indications approved will probably increase coming years. Rese...

CONTEXT AND OBJECTIVE Free circulating Epstein-Barr virus (EBV) DNA is often present in the plasma of Hodgkins disease patients. The aim here was to evaluate the prevalence of this finding, its correlation with the immunohistochemical expression of LMP-1 (latent membrane protein 1) and the influence of other clinical factors. DESIGN AND SETTING Prospective study in two public tertiary institu...

This study aimed to assess the efficacy of a multimodality imaging approach for differentiating between primary extranodal non-Hodgkin's lymphoma (NHL) and squamous cell carcinoma (SCC) of the maxillary sinus. Twelve NHLs and 29 SCCs of the maxillary sinus were included. CT findings, MR signal intensities, apparent diffusion coefficients (ADCs), and maximum standardized uptake values (SUVmax) w...

DESCRIPTION A 47-year-old unemployed man presented with a 2-week history of shortness of breath, dry cough and fever despite normal inflammatory markers and negative blood cultures. There was no weight loss or night sweats. He was a non-smoker and had no other medical history. HIV testing and tumour markers were negative. Chest x-ray (figure 1A) showed what seemed to be a dense consolidation in...