We present the case of a 55 yr female who had recurrent severe hypoglycemic attacks with neuroglycopenic symptoms and altered sensorium including coma. The hypoglycemic episodes were not related to fasting. The hypoglycemia was hyperinsulinemic but all imaging modalities for insulinoma were negative. Selective arterial calcium stimulation test localized the lesion to splenic artery territory an...

A boy was born at 36 weeks' gestation weighing 2450 g. Though his Apgar score was 9 at birth, by the age of 48 hours he required artificial ventilation. He was deeply unconscious with complete lack of muscle tone, and non-ketotic hyperglycinaemia associated with secondary hypoplasia of the corpus callosum was confirmed by biochemical tests. The cranial ultrasound scan features correlated well w...

Diazoxide is a benzothiadiazine derivative, chemically closely related to thiazide diuretics but lacking diuretic activity. Fajans et al (1968) have recorded this agent's ability of supress insulin release from normal and abnormal islet cell tissue. This property was exploited in the treatment of our patient, a 16 week-old infant with severe, prolonged symtomatic hypoglycaemia. Unfortunate adve...

Background: Hypoglycemia is a condition when blood glucose level is lower than 70 mg/dl in people without diabetes. The symptoms of hypoglycemia include tachycardia, sweating, pallor, pupillary dilatation. Hypoglycemia is a non-lethal and often preventable clinical problem in non-diabetic patients that can occur during fasting or after dining. Case presentation: A 52 years old man referred to ...

BACKGROUND Non-severe hypoglycemia reduces well-being, lowers quality of life, reduces productivity and increases treatment costs. The non-severe hypoglycemia rate, attributable to sulfonylurea (SU) utilization compared with newer classes such as SGLT2-I, could be of clinical significance. OBJECTIVES To explore the non-severe hypoglycemia risk difference (RD) for SU use compared with SGLT2-I ...

AIMS We sought to develop descriptions of health states associated with daytime and nocturnal hypoglycemia in a structured fashion from the patient's perspective under different combinations of severity and frequency of hypoglycemic events. METHODS An expert meeting followed by two patient focus groups was used to develop comprehensive descriptions of acute consequences of severe and non-seve...

Hypoglycemia has a serious impact on the morbidity, mortality and quality of life people with Diabetes Mellitus (DM). To prevent or reduce risk hypoglycemia, education is very important, including identification detection causes, prevention efforts early treatment at home. The use mobile applications strongly supports independent health management because it easily accessible, portable, low cos...