نتایج جستجو برای: non physician clinician npc

تعداد نتایج: 1384829  

Journal: :International journal of oncology 2014
Lee Fah Yap Munirah Ahmad Muhammad Mamduh Ahmad Zabidi Tai Lin Chu San Jiun Chai Hui Min Lee Paul Vey Hong Lim Wenbin Wei Christopher Dawson Soo-Hwang Teo Alan Soo Beng Khoo

The molecular events that drive the progression of Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) are still to be elucidated. Here, we report for the first time the pathogenic significance of an NPC-associated gene, wingless-type MMTV integration site family, member 5A (WNT5A) and the contribution of EBV to its expression. WNT5A is a representative Wnt protein that activates...

2013
MAELINDA DAKER SAATHEEYAVAANE BHUVANENDRAN MUNIRAH AHMAD KENZO TAKADA ALAN SOO-BENG KHOO

Nasopharyngeal carcinoma (NPC) is a unique tumour of epithelial origin with a distinct geographical distribution, closely associated with the Epstein‑Barr virus (EBV). EBV‑encoded RNAs (EBERs) are small non‑polyadenylated RNAs that are abundantly expressed in latent EBV‑infected NPC cells. To study the role of EBERs in NPC, we established stable e...

2009
J. Totenhagen I. Borbon E. Yoshimaru C. Howison R. P. Erickson T. P. Trouard

Introduction Niemann-Pick Type C (NPC) disease is a rare autosomal recessive neurodegenerative disease which involves impaired transport of intracellular lipids and accumulation of unesterified cholesterol in lysosomes and late endosomes in cells throughout the body [1]. NPC disease symptoms, including progressive ataxia, developmental dystonia, and dementia, often appear in the first decade of...

2014
Claire Kendall James Maskalyk Anita Palepu

Claire Kendall, MD, is Deputy Editor at Open Medicine; an Associate Professor with the Department of Family Medicine, University of Ottawa; Clinician Investigator at the C.T. Lamont Primary Health Care Research Centre, Élisabeth Bruyère Research Institute; and a practising family physician with the Riverside Campus Family Health Team, Ottawa, Ontario. James Maskalyk, MD, is an Associate Editor ...

2007
Stephanie B. Linek Daniel Schwarz Ganit Hirschberg Michael Kickmeier-Rust Dietrich Albert

The basic idea of game-based learning is the fusion of fun and learning by using the motivational potential of video games in the educational context. Thus, the design of an educational game should be adaptive not only to the learner’s cognitive abilities, but also to the individual preferences of the player. Especially the design of the non-player character (NPC) that takes the role of a teach...

2016
Yan-Yan Liu Shao-Jun Lin Yuan-Yuan Chen Li-Na Liu Liu-Bin Bao Lin-Quan Tang Jing-Song Ou Zhi-Gang Liu Xiao-Zhong Chen Yan Xu Jun Ma Anthony T. Chan Ming Chen Yun-Fei Xia Wan-Li Liu Yi-Xin Zeng Hai-Qiang Mai Mu-Sheng Zeng Jian-Ji Pan Xing Zhang

PURPOSE We aimed to assess the prognostic value of pretreatment high density lipoprotein cholesterol (HDL-C) levels in patients with nasopharyngeal carcinoma (NPC) and investigate the possible biological effects of these lipoproteins on NPC cells in vitro. EXPERIMENTAL DESIGN We examined the prognostic value of pretreatment HDL-C levels in 2443 patients with non-metastatic NPC from three inde...

Journal: :iranian journal of cancer prevention 0
ali safavi naini department of otolaryngology, head and neck surgery, tracheal research center, masih daneshvari hospital, shahid beheshti university of medical sciences, tehran, iran nasim raad department of otolaryngology, head and neck surgery, tracheal research center, masih daneshvari hospital, shahid beheshti university of medical sciences, tehran, iran jahangir ghorbani department of otolaryngology, head and neck surgery, tracheal research center, masih daneshvari hospital, shahid beheshti university of medical sciences, tehran, iran samira chaibakhsh department of biostatistics, p h. d in biostatistics shahid beheshti university of medical sciences, tehran, iran rashid ramezani-daryasar department of health of iran, expert of non-communicable disease, cancer of cdc.

background : nasopharyngeal carcinoma (npc) is known as a highly distinct kind of head and neck cancer. this distinction is due to its clinical presentation, epidemiology, outcome, and treatment. there have not been any reports of epidemiological analysis of npc in iran. the aim of this study is to evaluate the incidence rates and trends of nasopharyngeal carcinoma in the iranian population dur...

2015
Han Wen Mak Shan Hui Lee Jeremy Chee Ivan Tham Boon Cher Goh Siew Shuen Chao Yew Kwang Ong Kwok Seng Loh Chwee Ming Lim

BACKGROUND Nasopharyngeal cancer (NPC) is endemic among Chinese populations in Southeast Asia. However, the outcomes of non-Chinese NPC patients in Singapore are not well reported. AIM To determine if non-Chinese NPC patients have a different prognosis and examine the clinical outcomes of NPC patients in a multi-ethnic society. METHODS Retrospective chart review of 558 NPC patients treated ...

2011
Sayeeda Rahman Md Anwarul Azim Majumder Sami F Shaban Nuzhat Rahman Moslehuddin Ahmed Khalid Bin Abdulrahman Urban JA D’Souza

The rapid development of new drugs, therapies, and devices has created a dramatic increase in the number of clinical research studies that highlights the need for greater participation in research by physicians as well as patients. Furthermore, the potential of clinical research is unlikely to be reached without greater participation of physicians in research. Physicians face a variety of barri...

2010
Cong-Xiang Shen Zhong Wen Yu-Hong Qian Shao-Feng Mu Xiao-Fang Guan

BACKGROUND/AIM To explore the therapeutic effects of thymidine kinase (TK) expressed by enhanced vector pGL3-basic- hTERTp-TK-EGFP-CMV driven by human telomerase reverse transcriptase promoter (hTERTp) as well as cytomegalovirus immediate early promoter enhancer (CMV). MATERIALS/METHODS Enhanced TK-EGFP expression was confirmed by fluorescent microscopy, real time PCR and telomerase activity....

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