Vibrio qinghaiensis sp.-Q67 (Vqin-Q67) is a freshwater luminescent bacterium that continuously emits blue-green light (485 nm). The bacterium has been widely used for detecting toxic contaminants. Here, we report the complete genome sequence of Vqin-Q67, obtained using third-generation PacBio sequencing technology. Continuous long reads were attained from three PacBio sequencing runs and reads ...

it has been well documented that preeclampsia (pe) has a common etiological background, but little is known about its linkage at the molecular level.non- coding rnas are critical posttranscriptional regulators ofgene expression.  this study was performed to determine whether peis associated with alterations in placental non-codingrnas expression. microrna(mir)-155-5p and long non-coding rna (ln...

A complex interaction occurs between cancer cells and the extracellular matrix (ECM) in tumour microenvironment (TME). In this study, expressions mutational profiles of 964 ECM-related genes their correlations with patient overall survival (OS) neuroblastoma, an aggressive paediatric malignancy, were investigated using cBioPortal PCAT databases. Furthermore, extended networks comprising protein...

It is a challenge to classify protein-coding or non-coding transcripts, especially those re-constructed from high-throughput sequencing data of poorly annotated species. This study developed and evaluated a powerful signature tool, Coding-Non-Coding Index (CNCI), by profiling adjoining nucleotide triplets to effectively distinguish protein-coding and non-coding sequences independent of known an...

Host-virus interaction via host cellular components has been an important field of research in recent times. RNA interference mediated by short interfering RNAs and microRNAs (miRNA), is a widespread anti-viral defense strategy. Importantly, viruses also encode their own miRNAs. In recent times miRNAs were identified as key players in host-virus interaction. Furthermore, viruses were shown to e...

RNA was first explored and understood as a messenger molecule, relaying DNA encodings of amino acids during protein synthesis. Beyond messenger RNA, however, a class of RNA known as non-coding RNA plays fundamental roles in transcriptional and translational gene regulation. As the biological mantra goes, form fits function, and these regulatory roles depend on the 3-D structure of the RNA molec...

Non-coding RNAs (ncRNAs) are frequent and prevalent across the taxa. Although individual non-coding loci have been assigned a function, most are uncharacterized. Their global biological significance is unproven and remains controversial. Here we investigate the role played by ncRNAs in the stress response of Schizosaccharomyces pombe. We integrate global proteomics and RNA sequencing data to id...