800x600 hepatitis b virus (hbv) infection is the main cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma (hcc). several factors such as serum hbv dna level, genotype and specific viral mutations have been clarified to determine disease progression of chronic hepatitis b. among these, mutations can also occur in chronic hbv patients with antiviral treatment such as lamivudine the...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 jejunal diverticula have a prevalence of approximately 1% in the general population. perforation of jejunal diverticulum is a rare. clinically this diagnosis may be easily confused with other causes of an acute abdomen. in the article, we discuss a 74-year–old man with a 2-day history of constipation and left–sided abdominal ...

The five adaptor protein (AP) complexes function in cargo-selection and coat-recruitment stages of vesicular transport in eukaryotic cells. Much of what we know about AP complex function has come from experimental work using Saccharomyces cerevisiae as a model. Here, using a combination of comparative genomic and phylogenetic approaches we provide evolutionary context for the knowledge gained f...

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Voxel-based morphometry (VBM) is a hypothesis-free, whole-brain, voxel-by-voxel analytic method that attempts to compare imaging data between populations. Schizophrenia studies have utilized this method to localize differences in diffusion tensor imaging (DTI) derived fractional anisotropy (FA), a measure of white matter integrity, between patients and healthy controls. The number of publicatio...