نتایج جستجو برای: noninvasive samples
تعداد نتایج: 451473 فیلتر نتایج به سال:
Several retrospective and prospective studies have shown that genomic alterations in Estrogen-receptor one (ESR1) can be characterized not only tissue samples but also by sequencing circulating tumor DNA (ctDNA) liquid biopsy. Therefore, biopsy is a potential noninvasive surrogate for This meta-analysis was designed to compare the prevalence of ESR 1 mutation detected with A pooled published be...
background: solid ameloblastoma (sab) is an invasive tumor which infiltrates adjacent normal tissues. adenomatoid odontogenic tumor is a noninvasive tumor and never infiltrates surrounding normal tissues. the purpose of this study was to determine the biological behavior of these two epithelial odontogenic neoplasm by detecting ki-67 and bcl-2, which are mitotic and anti apoptotic markers respe...
BACKGROUND Currently very few noninvasive molecular genetic approaches are available to determine zygosity for twin pregnancies in clinical laboratories. This study aimed to develop a novel method to determine zygosity by using maternal plasma target region sequencing. METHODS We constructed a statistic model to calculate the possibility of each zygosity type using likelihood ratios ( Li ) an...
Noninvasive diagnosis and prognostication of acute cellular rejection in the kidney allograft may help realize the full benefits of kidney transplantation. To investigate whether urine metabolites predict kidney allograft status, we determined levels of 749 metabolites in 1516 urine samples from 241 kidney graft recipients enrolled in the prospective multicenter Clinical Trials in Organ Transpl...
Although the early diagnosis of gastric cancer provides the opportunity for curative endoscopic resection, comprehensive screening endoscopy would be invasive and expensive. To date, there is a complete absence of clinically useful gastric cancer biomarkers. With the goal of discovering noninvasive biomarkers for the early diagnosis of gastric cancer, we have conducted a case-control study usin...
context prenatal testing aims to identify fetal chromosomal and genetic disorders prior to delivery. current invasive procedures such as amniocentesis and chorionic villus sampling (cvs) pose a risk to mother and fetus and such diagnostic procedures are available only to high-risk pregnancies, which limits aneuploidy detection rate. the identification of cell-free fetal dna (cffdna) in maternal ...
background: fetal heart rate (fhr) extracted from abdominal electrocardiogram (ecg) is a powerful non-invasive method in appropriately assessing the fetus well-being during pregnancy. despite significant advances in the field of electrocardiography, the analysis of fetal ecg (fecg) signal is considered a challenging issue which is mainly due to low signal to noise ratio (snr) of fecg. objective...
The detection of pancreatic elastase 1 in stool samples has become the noninvasive gold standard for the diagnosis of pancreatic insufficiency in humans. Accordingly, the development of a sandwich-ELISA specific for canine pancreatic elastase 1, based on monoclonal antibodies, is presented here. The test has a detection range of 4-240 microg canine pancreatic elastase l/g feces. The intraassay ...
Genetic susceptibility and Epstein-Barr virus (EBV) infection are important etiological factors in nasopharyngeal carcinoma (NPC). In this study, in southern China, where NPC is endemic, a single nucleotide polymorphism (SNP) in the EBV-encoded RPMS1 gene (locus 155391: G > A [G155391A]) and seven host SNPs (rs1412829, rs28421666, rs2860580, rs2894207, rs31489, rs6774494, and rs9510787) were co...
Background: Fetal sex determination is useful for families at risk of X-linked disorders, such as Duchenne muscular dystrophy, adrenal hypoplasia, hemophilia. At first, this could be obtained through invasive procedures such as amniocentesis and chorionic villus sampling, having a 1% risk of miscarriage. Since the discovery of cell-free fetal DNA (cffDNA) in maternal plasma, noninvasive prenata...
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