نتایج جستجو برای: nonstructural protein 3

تعداد نتایج: 2817426  

Journal: :Current issues in molecular biology 2007
David N Frick

The C-terminal portion of hepatitis C virus (HCV) nonstructural protein 3 (NS3) forms a three domain polypeptide that possesses the ability to travel along RNA or single-stranded DNA (ssDNA) in a 3' to 5' direction. Fueled byATP hydrolysis, this movement allows the protein to displace complementary strands of DNA or RNA and proteins bound to the nucleic acid. HCV helicase shares two domains com...

Journal: :The Journal of general virology 2003
Alain Kohl Anne Bridgen Ewan Dunn John N Barr Richard M Elliott

The genome of Bunyamwera virus (BUN) consists of three segments of single-stranded RNA of negative polarity. The smallest segment, S, encodes the N protein and a nonstructural protein called NSs. We recently described a mutant virus (BUNdelNSs) that does not express NSs but overexpresses N and grows to lower titres than wild-type (wt) BUN. Here we report a BUNdelNSs variant that expresses lower...

Ali Ali Teimoori Gholamreza Haqshenas Hadi Razavinikoo Hoorieh Soleimanjahi, Taravat Bamdad, Zahra Goodarzi,

Objective(s): The rotavirus nonstructural protein 4 (NSP4) is responsible for the increase in cytoplasmic calcium concentration through a phospholipase C-dependent and phospholipase C-independent pathways in infected cells. It is shown that increasing of intracellular calcium concentration in rotavirus infected cells is associated with the activation of some members of protein kinases family su...

2010
David R. Gretch Stephen J. Polyak Kevin C. Klein Ikuo Shoji Tatsuo Miyamura Cheng Kao Linda B. Couto David N. Frick

The C-terminal portion of hepatitis C virus (HCV) nonstructural protein 3 (NS3) forms a three domain polypeptide that possesses the ability to travel along RNA or single-stranded DNA (ssDNA) in a 3' to 5' direction. Fueled by ATP hydrolysis, this movement allows the protein to displace complementary strands of DNA or RNA and proteins bound to the nucleic acid. HCV helicase shares two domains co...

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