Glyoxalase I has been purified from the livers of normal DBA/1J mice (565-fold) and mice bearing a lymphosarcoma (348-fold). There was a significant difference in the fractionation patterns of the glyoxalase I activities from the two sources. Molecular weight determinations for which Sephadex gel filtration was used were conducted on the purified enzymes. The estimated molecular weights are 48,...

Glutathione S-transferase (GST) enzyme activity, GST isoenzyme composition and glutathione (GSH) concentration were assessed in normal and squamous cell carcinoma specimens of 14 patients with oral or oropharyngeal cancer and 11 patients with laryngeal cancer. Comparing malignant with normal oral/oropharyngeal tissues, no significant differences in GSH content, GST enzyme activity or isoenzyme ...