OBJECTIVE Volume replacement in septic patients improves hemodynamic stability. This effect can reduce the inflammatory response. The objective of this study was to evaluate the effect of 7.5% hypertonic saline solution versus 0.9% normal saline solution for volume replacement during an inflammatory response in endotoxemic rats. METHODS We measured cytokines (serum and gut), nitrite, and lipi...

BACKGROUND Acute kidney injury (AKI) is a common and life-threatening complication following coronary artery bypass graft (CABG). Neutrophil gelatinase-associated lipocalin (NGAL) and Cystatin C have shown to be good predictive factors for AKI. Recently, there has been a growing interest in the use of hypertonic saline in cardiac operations. The purpose of this study was to evaluate the prophyl...

Urinary sodium output increases in the first several days of fasting both in humans and rabbits. The major causal factor of the fasting-induced natriuresis was proposed to be glucagon (1), but the mechanism remains obscure. We have recently observed that fasting for one to four days resulted in the negative sodium balance in rats provided a low salt diet and saline (2). The fasting-induced natr...

BACKGROUND Most acute wheezing episodes in preschool children are associated with rhinovirus. Rhinovirus decreases extracellular adenosine triphosphate levels, leading to airway surface liquid dehydration. This, along with submucosal edema, mucus plaques, and inflammation, causes failure of mucus clearance. These preschool children do not respond well to available treatments, even oral steroids...

The effect of different storage solutions on surface topography of mineral trioxide aggregate (MTA) and new experimental cement (NEC) as root-end fillings was investigated. Twenty-four single-rooted teeth were cleaned, shaped and obturated in a same manner. After root-end resection, 3-mm deep root-end cavities were ultrasonically prepared. Samples were randomly divided into four test groups (A1...

SRIRAM POTHAPREGADA Department of Pediatrics, Indira Gandhi Medical College and Research Institute, Pondicherry 605 009, [email protected] REFERENCES 1. Mothers feed newborn babies donkey milk. Times of India 2008 May 6; Chennai: Page 6(Col-1) 2. Curative donkey milk in high demand in Chennai. Times of India 2011 Jan 25; Chennai: Page 4(Col2). 3. Haroon S, Das JK, Salam RA, Imdad A, Bhutt...

1. By introducing intravenously into dogs a solution of 5 per cent. ether in normal saline (0.9 per cent.), a satisfactory surgical anesthesia can be produced. 2. Associated with this anesthesia a glycosuria occurs in healthy adult dogs fed on a meat diet. 3. Normal saline (0.9 per cent.) introduced in exactly the same manner does not cause a glycosuria. 4. The glycosuria is, in general, associ...

The aim of this study was to determine whether exposure of human articular cartilage to hyperosmotic saline (0.9%, 600 mOsm) reduces in situ chondrocyte death following a standardised mechanical injury produced by a scalpel cut compared with the same assault and exposure to normal saline (0.9%, 285 mOsm). Human cartilage explants were exposed to normal (control) and hyperosmotic 0.9% saline sol...