From the second half of the twentieth century, advances in biological and psychopharmacological research seemed to promise a swift discovery of an organic basis of psychiatric diseases. Today we know that biological research in psychiatry is not a success story. This may be due to the complicated character of psychiatric disorders, where it is difficult to establish a unified model of the disea...

Nuclear medicine is a diagnostic imaging modality that is used to obtain clinical information about most of the major tissues and organs of the body. Diagnostic information is obtained from the way the tissues and organs process radiolabeled compounds (radiopharmaceuticals). The radiopharmaceutical is typically administered to the patient though an intravenous injection. The radiopharmaceutical...

Digitalfilteringisa powerfulmathematicaltechniqueincomputeranalysisofnu clear medicinestudies.The basic conceptsof object-domainand frequency-do main filteringare presentedin simple,largelynonmathematicalterms. Computa tional methodsare describedusingboth the Fouriertransformand convolution techniques.Thefrequencyresponseisdescribedandusedto representthe behav br of several classes of filters. ...

Xenon-133 and xenon-127 were compared by performing ventilation studies with both radionuclides in 19 patients with a variety of lung diseases. Assessment of the counting rate over the chest, relative to the radioactivity in the lungs, permitted the evaluation of each isotope in terms of usable photons detected by a scintillation camera with a large field of view and ap propriate collimili ion....

A brief overview is provided of the history of the development of internal dose methods for use in nuclear medicine. Basic methods of internal dosimetry and the systems that have been developed for use in nuclear medicine are described. The development of the MIRD system and the International Radiopharmaceutical Dosimetry Symposium series is outlined. The evolution of models and tools for calcu...