Tomato leaf curl Bangalore virus (ToLCBV) (Geminiviridae) causes the economically important tomato disease (ToLCVD), and is transmitted by whitefly, Bemisia tabaci (Gennadius) (Aleyrodidae: Hemiptera). Successful transmission of insect requires safe translocation through different barriers inside vector. During translocation, viral coat protein will interact with many whitefly proteins, while a...

Treatment of adenovirus type 5-infected cells with daunorubicin (D) at a concentration of 0-05 ug/ml reduced the in vitro virus infectivity by six logs. Mature virus particles were not detected in extracts of D-treated cells by density gradient centrifugation and the low level of infectivity observed appeared to be due to free nucleoprotein. Virus components produced in the D-treated cells were...

Telomeres are the nucleoprotein structures at the end of linear eukaryotic chromosomes required for genome stability. Telomerase is the specialized enzyme deputed to their elongation. Maintenance of a proper telomere structure, an accurate regulation of telomerase biogenesis and activity, as well as a correct telomere-telomerase interaction and a faithful telomeric DNA replication are all proce...

Telomeres are nucleoprotein structures that shelter the ends of linear chromosomes from being inappropriately recognized as DNA double-strand breaks. New work has revealed that Apollo, a nuclease previously implicated in DNA repair, also has a role in safeguarding telomeres during S phase.

The ends of eukaryotic chromosomes have long been defined as structures that must avoid being detected as DNA breaks. They are protected from checkpoints, homologous recombination, end-to-end fusions, or other events that normally promote repair of intrachromosomal DNA breaks. This differentiation is thought to be the consequence of a unique organization of chromosomal ends into specialized nuc...

The influenza A virus genome consists of eight RNA segments that associate with the viral polymerase proteins (PB1, PB2, and PA) and nucleoprotein (NP) to form ribonucleoprotein complexes (RNPs). The viral NS1 protein was previously shown to associate with these complexes, although it was not clear which RNP component mediated the interaction. Using individual TAP (tandem affinity purification)...

The antiprotein in an antipneumococcus horse serum resulting from intravenous injections of infected pleural exudate showed a precipitin type of reaction with pneumococcus nucleoprotein rather than the antitoxin type of response.

Fixed chromosome preparations subjected to treatments such as pH 9 (I) or trypsin hydrolysis (2) and stained with Giemsa's demonstrate similar banding patterns irrespective of the pretreatments used. It has been shown that this phenomenon is the result of modifications of DNA-protein and protein-protein associations which alter dye interaction (3-5). It appears that only Giemsa's or related sta...