OBJECTIVE MALT lymphomas are a group of extranodal indolent lymphomas that usually present as stage IE. To clarify clinical features, treatment alternatives and outcomes, we evaluated 38 patients treated with chemotherapy or radiotherapy between 2000 and 2011. PATIENTS AND METHODS MALT lymphoma patients identified according to WHO classification and treated at KCCC between 2000 and 2011 were ...

PURPOSE Mucosa-associated lymphoid tissue (MALT) lymphoma comprises 7% of all newly diagnosed non-Hodgkin's lymphomas and is therefore among the most common lymphoma entities. Monoclonal gammopathy due to production of a monoclonal immunoglobulin by lymphoma cells is a well-known phenomenon associated with various types of B-cell non-Hodgkin's lymphomas. The objective of the present study was t...

Gastric marginal zone B-cell lymphoma of MALT type (MALT lymphoma) arises in the context of chronic inflammation induced by the bacterial pathogen Helicobacter pylori. Although generally considered an indolent disease, MALT lymphoma may transform to gastric diffuse large B-cell lymphoma (gDLBCL) through mechanisms that remain poorly understood. By comparing microRNA expression profiles of gastr...

AIMS To evaluate the chromosomal translocation t(11;18)(q21;q21) in gastrointestinal lymphomas. METHODS A possible API2-MLT fusion transcript specific to t(11;18)(q21;q21) was examined by means of reverse transcription-polymerase chain reaction (RT-PCR) in tumours from 47 cases of primary gastrointestinal lymphoma (28 low grade mucosa associated lymphoid tissue (MALT) lymphomas, four low grad...

We read with great interest the article by González-Juanatey et al. on the cost-effectiveness of the new oral anticoagulant dabigatran compared with conventional oral anticoagulant therapy (OAT) in patients with nonvalvular atrial fibrillation. This study consisted of a simulation using modern computer models applied to the Spanish setting. It concluded that dabigatran would be an effective str...

Phytochrome A is a member of a plant regulatory photoreceptor family (1). The down-regulation by phytochrome of the transcription of its own PHYA3 gene, is one of the most rapid light-mediated effects on transcription reported to date in plants (2). Two positive elements designated PE1 (-367 bp to -346 bp) and PE3 (-111 bp to -81 bp) necessary for high level expression of the oat PHYA3 gene, we...

We read with great interest the article by González-Juanatey et al. on the cost-effectiveness of the new oral anticoagulant dabigatran compared with conventional oral anticoagulant therapy (OAT) in patients with nonvalvular atrial fibrillation. This study consisted of a simulation using modern computer models applied to the Spanish setting. It concluded that dabigatran would be an effective str...

Background Deficiency of available forms of phosphorus is common in most soils and causes reduction of crop plants growth and yield. Recently, model plants responses to phosphate (Pi) deficiency have been intensively studied. However, acclimation mechanisms of cereals like oat (Avena sativa L.), to low Pi stress remains not fully understood. Oat plants have been usually cultured on poor soils, ...

Ornithine aminotransferase (L-ornithine: 2-oxoacid aminotransferase, OAT, EC 2.6.1.13) plays crucial physiological roles in amino acid metabolism because this enzyme is at the crossroad of several pathways including those of L-arginine, L-ornithine, L-glutamate, Lglutamine, and L-proline. Specifically, OAT catalyzes the transamination of L-ornithine in the presence of α-ketoglutarate to produce...

Background and Objective: Minor dental surgery is invasive and hemorrhagic. Thus, in patients treated with anticoagulants, the bleeding risk related to these invasive procedures is concerning. The aim of this meta-analysis is to evaluate this risk by comparing the post-operative bleeding rates of oral anticoagulation treatment (OAT) patients (without interrupted or altered anticoagulant intake)...