RESEARCH ARTICLE A New Method to Prescribe Wedges Custom Made For Individuals With Transfemoral Amputation Using Principal Component Analysis Denise Paschoal Soares , Marcelo Peduzzi de Castro, Emília Mendes and Leandro Machado Center of Research, Education, Innovation and Intervention in Sport, Faculty of Sport, University of Porto, Portugal Porto Biomechanics Laboratory,University of Porto, P...

The authors present a historical review of spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD), the most common form of spinocerebellar ataxia in Brazil, and consider the high frequency of cases in families from Itajaí, a city on the coast of the state of Santa Catarina with a large population of Portuguese/Azorean descent.

BACKGROUND AND PURPOSE Machado-Joseph disease (MJD/SCA3) is the most frequent spinocerebellar ataxia, characterized by brainstem, basal ganglia and cerebellar damage. Few magnetic resonance imaging based studies have investigated damage in the cerebral cortex. The objective was to determine whether patients with MJD/SCA3 have cerebral cortex atrophy, to identify regions more susceptible to dama...

30 years ago already, the then nuclear research center in Karlsruhe publicized experimentally determined dimensions and shapes of various nuclei. Apart from the obvious spherical shape, cylindrical and elliptical nuclei had also been found. Such experimental results have to be compared with calculations. Not only the number of p+ and n± involved, but also spin, direction of rotation, and nuclea...

La investigación se encuentra sustentada en las Memorias de Gobierno disponibles el Archivo General del Poder Ejecutivo Estado Oaxaca. Documentamos impulso que tuvo la producción café a través iniciativas Matías Romero Avendaño finales siglo diecinueve. Funcionario público y empresario cafeticultor oaxaqueño plasmó su experiencia diversos textos. Encontramos esta actividad agrícola un impacto p...

Performance and Results of Hifocus 1j ® Cochlear Implants Vanessa Brito Campoy Rocha1*, Silvia Badur Curi1, Walter Adriano Bianchini1, Alexandre Caixeta Guimarães1, Jorge Rizzato Paschoal1, Guilherme Machado de Carvalho1 Department of Ear, Nose, Throat and Head & Neck Surgery, Otology, Audiology and Implantable Ear Prostheses, São Paulo, Campinas University, Brazil SOJ Surgery Open Access Resea...

Maria Eugénia Mata 1,† and Jose Tenreiro Machado 2,*,† 1 Faculdade de Economia, Nova School of Business and Economics, Campus de Campolide, Lisbon 1099-032, Portugal; [email protected] 2 Department of Electrical Engineering, Institute of Engineering, Polytechnic Institute of Porto, Porto 4249-015, Portugal * Correspondence: [email protected]; Tel.: +351-22-8340500 † These authors contributed equa...

Segregation ratio distortion (SRD) with preferential transmission of expanded CAG alleles has been reported in Machado-Joseph disease (MJD/SCA3), spinocerebellar ataxia type I (SCA1), and dentatorubral-pallidoluysian atrophy (DRPLA). We have examined the transmission frequencies of alleles in normal heterozygotes at these disease loci in 377 pairs of twins and their parents and find no evidence...