this study investigated the effectiveness of cognitive – behavioral therapy, drug tehrapy, and their combination in treating obsessive – compulsive disorder. twenty one patients with obsessive – compulsive disorder were randomly assigned to three groups: cognitive – behavioral , clomipramine, and combined cognitive – behavioral and clomipramine treatment groups. treatment outcomes were analyzed...

OBJECTIVE Serotonin reuptake inhibitors are frequently used in first-line treatments for patients with obsessive-compulsive disorder. Nevertheless, many of these patients do not respond well to initial therapy. The hypothesis of glutamatergic dysfunction in specific brain regions has been proposed in the pathophysiology of obsessive-compulsive disorder. This study was designed to evaluate the p...

INTRODUCTION Musical obsessions consist of intrusive recollections of music fragments that are experienced as unwanted. Otosclerosis is caused by an abnormal bone homeostasis of the otic capsule and represents a frequent cause of hearing impairment. Many conditions causing hearing loss have been associated with musical hallucinations, but the association between musical obsessions and hearing l...

One of the core behavioral features associated with obsessive compulsive symptomatology is the inability to inhibit thoughts and/or behaviors. Neuroimaging studies have indicated abnormalities in frontostriatal and dorsolateral prefrontal - anterior cingulate circuits during inhibitory control in patients with obsessive compulsive disorder compared with controls. In the present study, task perf...

Preview Enormous amounts of time and energy may be consumed by persons with obsessive-compulsive disorder, who think distressing thoughts and then feel compelled to act on them repeatedly. How common is obsessive-compulsive disorder? What are its typical clinical presentations? The authors of this article answer these questions and discuss pharmacologic and behavior therapy.

objective: serotonin reuptake inhibitors are frequently used in first-line treatments for patients ‎with obsessive-compulsive disorder. nevertheless, many of these patients do not ‎respond well to initial therapy. the hypothesis of glutamatergic dysfunction in specific ‎brain regions has been proposed in the pathophysiology of obsessive-compulsive ‎disorder. this study was designed to evaluate ...

The spectrum of obsessive-compulsive disorders has received a great deal of theoretical attention, but there has been relatively little associated empirical research. The purpose of this study was to compare three groups of patients; those diagnosed with hypochondriasis (HC, a proposed spectrum condition), obsessive-compulsive disorder (OCD) and those with both OCD and HC (OCD/HC). The results ...

Introduction Obsessive-compulsive disorders are complex pathologies causing a major psychosocial handicap. However, their association with disabling somatic pathology such as rheumatoid arthritis makes management more difficult. Objectives To investigate through case analysis and review of literature the between obsessive-compulsive disorder (OCD) rheumatological disorders. Methods We reported ...