Purpose. To review the postoperative seizure outcomes of patients that underwent surgery for epilepsy at King Faisal Specialist Hospital & Research Centre (KFSHRC). Methods. A descriptive retrospective study for 502 patients operated on for medically intractable epilepsy between 1998 and 2012. The surgical outcome was measured using the ILAE criteria. Results. The epilepsy surgery outcome for t...

We investigated post-ictal headaches (PIH) using a questionnaire to ascertain their characteristics and compare them among different types of epilepsy. The subjects consisted of 34 patients with occipital lobe epilepsy (OLE) and 75 patients with temporal lobe epilepsy (TLE). PIH occurred in 62% of OLE and 23% of TLE (P < 0.05). The quality of pain in PIH was 'steady' in 71% of OLE and 29% of TL...

Oleoyl-estrone (OE) is an adipose-derived signal that decreases energy intake and body lipid, maintaining energy expenditure and glycemic homeostasis. Glucocorticoids protect body lipid and the metabolic status quo. We studied the combined effects of OE and corticosterone in adrenalectomized female rats: daily OE gavages (0 or 10 nmol/g) and slow-release corticosterone pellets at four doses (0,...

We herein describe two cases of patients with epilepsy with occipital lobe cortical dysplasia who were studied with both MR spectroscopy and MR diffusion imaging in addition to conventional MR imaging. Greater diffusion abnormalities, as well as more marked decreases in N-acetylaspartate, were observed to occur in the patient harboring a low grade neoplasm within an area of cortical dysplasia t...

OBJECTIVE To identify the rate of successful antiepileptic drug (AED) withdrawal after resective surgery and the predictors of postwithdrawal seizure recurrence in patients with extratemporal epilepsy. METHODS We retrospectively analyzed the postoperative AED profile of 106 consecutive patients who had completed 2 or more years after resections involving frontal, parietal, and occipital lobes...

Background: Oleuropein (OE) is the most abundant biophenol compounds in olive leaves and its healthy effects as a strong antioxidant is well known. The oleuropein level in olives depends upon cultivated variety, climate, place, time and the method of extraction. In Lorestan province, many varieties of olive have been cultivated that the study of OE level in their leaves, as whilst sources of th...

OBJECTIVES In a study of patients with focal epilepsy the hypothesis was explored that different measurements of psychopathology are related to specific distributions of cerebral perfusion. METHODS Forty patients had SPECT performed with (99m)Tc-HMPAO. In addition, patients received a psychiatric evaluation with the following psychiatric questionnaires: the Beck depression inventory, the Leyt...

Journal of Neurology Neurosurgery & Psychiatry (ISSN No: 0022-3050) is published monthly by BMJ Publishing Group and distributed in the USA by Mercury International Ltd. as mailing agent. Periodicals postage paid at Rahway, NJ. POSTMASTER: send address changes to Journal of Neurology Neurosurgery & Psychiatry, Mercury International Ltd, 365 Blair Road, Avenel, NJ, 07001, USA. Editorial commenta...

Arteriovenous malformation (AVM) of the brain is one of the important pathologic conditions which cause intracerebral or subarachnoid hemorrhage, epilepsy, or chronic cerebral ischemia. The spontaneous regression of cerebral AVM is reported to be very rare and more likely to occur when the AVM is small, is accompanied by hemorrhage, and has fewer arterial feeders. We report a case of right occi...

Objectives-In a study of patients with focal epilepsy the hypothesis was explored that different measurements of psychopathology are related to specific distributions of cerebral perfusion. Methods-Forty patients had SPECT performed with 9hnTc-HMPAO. In addition, patients received a psychiatric evaluation with the following psychiatric questionnaires: the Beck depression inventory, the Leyton o...