Seizures are a symptom and not a disease. A seizure is the result of an abnormal electrical discharge of a collection or group of living but damaged or abnormal neurons. When the group of neurons is in the cerebral cortex, a focal or partial seizure occurs , producing abnormal activity related to that part of the brain. The victim may experience a focal jerking or focal numbness, or flashing li...

The site of origin of complex partial seizures (CPS) is predominantly in the temporal lobe, but frontal, parietal, and occipital lobes may also be involved. In order to correlate clinical behaviours with either a temporal or frontal site of origin, we analysed 211 seizures occurring during invasive monitoring in 26 patients with temporal lobe epilepsy (TLE) and in eight patients with frontal lo...

The symptomatology of auras and seizures is a reflection of activation of specific parts of the brain by the ictal discharge, the location and extent of which represent the symptomatogenic zone. The symptomatogenic zone is presumably, though not necessarily, in close proximity to the epileptogenic zone, the area responsible for seizure generation, the complete removal or disconnection of which ...

BACKGROUND Isolated sulfite oxidase deficiency (ISOD), caused by mutations in SUOX gene, is an autosomal recessive disease manifesting with early onset seizures, developmental delay, microcephaly, and spasticity. It mimics hypoxic-ischemic encephalopathy (HIE) the neonatal period characterized progressive severe neurological impairment due to accumulation of toxic metabolites. CASE This report ...

Case presentation: A previously healthy full term 4 month-old boy, presented by 1 months with tonic jerks of the upper limbs and slight behavior arrest. He had no signs infection history recent vaccination. These became daily, more intense, lateralized associated oral automatisms blinking. They a very brief duration, mostly 20–30 seconds each. EEG showed bilateral temporo-occipital sharp transi...

Case presentation: A 12-year-old female patient presents a 5-day history of fever and severe frontal occipital headache associated with vomiting, nocturnal awakenings, vertigo, phonophobia. She evolved dysarthria, decreased level consciousness, left hemiparesis followed by systemic arterial hypertension, bradycardia 8 episodes focal seizures. On neurological examination, she was alert, lucid, o...

Introduction. Gabapentin is a recently introduced antiepileptic drug [l]. Gabapentin is now widely prescribed for the management of neuropathic pain [2]. Designed to mimic GABA, its mechanism c! action remains elusive [3]. Daily use of gabapentin is associated with above normal occipital lobe GABA in those patients whose seizure control improved [4, 51. Vigabatrin is one of the most potent of t...

STUDY DESIGN Randomized controlled trial. OBJECTIVE The aim of the study was to compare and contrast the restrictiveness and tissue-interface pressure (TIP) characteristics of 2 standard and 2 adjustable cervical collars. SUMMARY OF BACKGROUND DATA This study compared the restrictiveness and TIP of 4 commercially available cervical collars (2 standard and 2 adjustable). Adjustable collars o...

We are reporting a case of multifocal reversible leucoencephalopathy syndrome induced by chemotherapy based on Folfox-Bevacizumab regimen. A 44-year-old female, with no history of hypertension, received a chemotherapy based on Folfox-Bevacizumab for her metastatic colon cancer (5 FU: 325 mg/m(2) d1 by intravenous infusion, Oxaliplatin 80 mg/m(2) d1, and Bevacizumab: 7.5 mg/Kg d1). During the fo...

Schizencephaly is a rare malformation of the central nervous system defined as a gray matter-lined cleft filled with cerebrospinal fluid that extends from the pial surface to the ventricle. Few cases of association with psychosis were reported in the scientific literature. We present a case of a 46-year-old woman, admitted into a psychiatric hospital with crises of psychomotor agitation, disorg...