OBJECTIVE Female sex is considered a significant risk in cardiac surgery and is included in the majority of scores for risk assessment. However, the evidence is controversial and older women undergoing cardiac surgery have not specifically been investigated. We assessed the influence of female sex on surgical risk (30-day mortality) in a secondary analysis of the GOPCABE trial (German Off-Pump ...

Avoiding the morbidity of cardiopulmonary bypass should theoretically reduce the incidence of organ dysfunction and lead to improved patient outcomes. Recently, cardiac mechanical stabilization techniques were developed, facilitating on-pump CABG (OPCAB). The use of CPB may influence the economic outcome, while maintaining quality of care and patient satisfaction. MEDLINE, EMBASE, Cochrane Cont...

Coronary artery bypass grafting (CABG) is a routine procedure, traditionally performed via median sternotomy access on the arrested heart with use of cardiopulmonary bypass (onpump). It is the clinical gold standard for myocardial revascularization in patients with multivessel coronary heart disease but remains associated with significant morbidity and mortality (Borst & Gründeman, 1999). Over ...

n engl j med 361;19 nejm.org november 5, 2009 1899 served procedural mortality rates for both offpump and on-pump CABG were excellent and well below those predicted according to standard risk models. Third, neurocognitive testing was performed in only half the survivors and, in contrast with the results of a previous study,7 did not show any longitudinal deficits in either surgical group. Final...

Objective: To evaluate and compare the pulmonary function in patients following onand off-pump coronary artery bypass grafting (CABG). Method: Thirty patients (mean age 56.76 ± 10.20 years) were allocated to two groups, according to the use or not of cardiopulmonary bypasses: group A (n=15) off-pump and group B (n=15) on-pump, with all patients undergoing preand post-operative evaluation of the...

Coronary artery disease remains a major cause of mortality and morbidity with systemic lupus erythematosus (SLE). We report two cases of coronary artery bypass grafting (CABG) associated with SLE. The first patient (a 45-year-old woman) underwent CABG operation for left main and two-vessel coronary disease using cardiopulmonary bypass. Successful CABG was done using off-pump technique in the se...

OBJECTIVE Cerebral injury, in both overt and subtle forms, is common following cardiac surgery. Current methods of assessment, most commonly neuropsychological testing, have several limitations and do not accurately define the anatomical and functional injury that occurs. We have assessed the degree of cerebral injury following on-pump and off-pump cardiac surgery using functional magnetic reso...

Gastrointestinal haemorrhage secondary to off-pump coronary artery bypass grafting (OPCABG) surgery is uncommon but lethal. We describe an 83-year-old male patient who developed gastrointestinal haemorrhage after successful off-pump CABG. He received intensive treatment, but further deteriorated following noradrenaline infusion, and subsequently died six days after surgery. Off-pump technique i...