Cytoplasmic inclusions containing TAR DNA-binding protein of 43 kDa (TDP-43) or Fused in sarcoma (FUS) are a hallmark of amyotrophic lateral sclerosis (ALS) and several subtypes of frontotemporal lobar degeneration (FTLD). FUS-positive inclusions in FTLD and ALS patients are consistently co-labeled with stress granule (SG) marker proteins. Whether TDP-43 inclusions contain SG markers is current...

Acetaminophen overdose is the most often cause of acute liver injury. The toxic mechanism is linked to formation of an active metabolite that reacts with glutathione generating acetaminophen-glutathione conjugate (APAP-SG). This compound has been recognized to be non-toxic generally. Our preliminary results showed, however, that APAP-SG could possess a toxic effect too. Therefore, the aim of ou...

in this paper, two new hamilton operators are defined and the algebra of dual split quaternions isdeveloped using these operators. it is shown that finite screw motions in minkowski 3-space can be expressedby dual-number ( 3×3 ) matrices in dual lorentzian space. moreover, by means of hamilton operators, screwmotion is obtained in 3-dimensional minkowski space 3r1

We report a simple synthesis of silver:glutathione (Ag:SG) clusters using a cyclic reduction under oxidative conditions. Two syntheses are described which lead to solutions containing well-defined Ag31(SG)19 and Ag15(SG)11 clusters that have been characterized by mass spectrometry. The optical properties of silver:glutathione (Ag:SG) cluster solutions have been investigated experimentally. In p...

The agents of sleeping sickness disease, Trypanosoma brucei complex parasites, are transmitted to mammalian hosts through the bite of an infected tsetse. Information on tsetse-trypanosome interactions in the salivary gland (SG) tissue, and on mammalian infective metacyclic (MC) parasites present in the SG, is sparse. We performed RNA-seq analyses from uninfected and T. b. brucei infected SGs of...

this study was aimed to evaluate the effects of diets containing some hot and coldtemperament herb seeds according to iranian traditional medicine (itm) on some metabolicparameters in acute (24 h) and sub-acute (7 day) experiments that were performed on rats. foreach experiment, effects of diets containing 10% herb seeds in category of hot (anise, fennel,ajowan) and cold (cucumber, watermelon, ...

Of 48 persons in a psychosocial rehabilitation program, 20 participated in an optional spirituality group (SG), while the other 28 did not. The recovery progress based on treatment goal attainment is compared between those participating and those not participating in the SG. Within 6 months, all of the SG participants (ioo%) achieved their goals, compared to 16 of the 28 individuals (57%) not i...