Abstract Background A microsponge delivery system (MDS) is an innovative and unique way of delivering drugs in a structured manner. Using drug delivery, regulated may now be achieved quickly easily. Main body MDS comprises porous microspheres ranging size from 5 to 300 microns, with large structure very tiny spherical shape. normally used deliver via topical channels, but they have recently sho...

Ophthalmic drug delivery to the posterior segment of eye has been challenging due complex ocular anatomy. Intravitreal injection drugs was introduced deliver therapeutic doses in segment. Different diseases including age-related macular degeneration, diabetic edema, retinal vein occlusions, uveitis, and cystoid among others, have historically treated with intravitreal corticosteroids injections...

AIMS To describe the number, type and location of ophthalmic companies and their associated product areas and indications. METHODS A retrospective, non-patient-based, observational review of ophthalmic pharmaceutical and device companies with a new product in development. Data was compiled by Internet searches. RESULTS We identified 190 companies currently developing ophthalmic products: 13...

This study aimed to optimize and evaluate a thermoresponsive ophthalmic in situ gel containing curcumin-loaded albumin nanoparticles (Cur-BSA-NPs-Gel). Albumin nanoparticles were prepared via a desolvation method, and the gels were prepared via a cold method. The central composite design and response surface method was used to evaluate the effects of varying Pluronic F127 and Pluronic F68 conce...

OBJECTIVE To assess whether the ophthalmic cases presenting at a Nigerian tertiary eye unit are appropriate for such level of care and also draw necessary implications for service delivery. METHODS Data on 1321 consecutive new patients that presented at the ophthalmic clinic of the University of Teaching Hospital, Ilorin, Nigeria between February and July 2005 were reviewed on demographics, r...