OBJECTIVES Novel therapeutics are an important part of ophthalmologists' armamentarium, and the risks and benefits of these therapies must be carefully evaluated. We sought to quantify the characteristics of the pivotal clinical trials supporting the regulatory approval of new ophthalmic drugs and medical devices. DESIGN Retrospective observational study. SETTING AND DATA SOURCE Medical rev...

The first edition of Ophthalmic Photography, published in 1997, was an ambitious undertaking that attempted to gather all aspects of retinal photography and angiography into one volume. The result was a comprehensive yet accessible book that has become a valuable reference for ophthalmic photographers worldwide. Five years have passed since publication of the first edition, and while the fundam...

The removal of diclofenac sodium ophthalmic solution as a viable pharmaceutical entity in September 1999 from the US market spurred considerable interest in the general safety and effectiveness of topical ophthalmic NSAIDs for treatment of anterior segment inflammation. In late 1999 the use of topical ocular NSAIDs declined in the US as a result of incidents involving corneal melts and toxicity...

the aim of this study is to formulate a novel ophthalmic nanosuspension (ons), an alternative carrier system to traditional colloidal carriers for controlled release (cr) of acyclovir (acv). in the present study, ons is employed to avoid some of major disadvantages of colloidal carriers systems such as instability in cul de sac and short half life by increasing efficiency of drug encapsulation ...

PURPOSE To evaluate visual field changes in patients with pituitary adenomas following trans-sphenoidal surgery. METHODS Eighteen patients with pituitary adenomas underwent a complete ophthalmic assessment and visual field analysis using the Humphrey Field Analyzer 30-2 program before and after trans-sphenoidal surgical resection at the Himalayan Institute of Medical Sciences over a one year ...

purpose: to compare ophthalmic artery velocity in eyes with nonarteritic anterior ischemic optic neuropathy (naion) with that of normal fellow eyes. methods: in this case-control study, 20 patients with unilateral naion and disease onset less than 8 weeks, were enrolled. using color doppler imaging, mean, maximum systolic and end diastolic ophthalmic artery velocities were evaluated. the result...

introduction: the main purpose of this study was to evaluate the prevalence of ophthalmic injuries associated with mid-facial fractures in patients admitted to shahid beheshti university hospital in babol, iran, from 2002 to 2012. materials and methods: a cross-sectional, retrospective study was undertaken to determine the prevalence of ophthalmic injuries associated with mid-facial fractures i...