In December 2012, the American College of Obstetricians and Gynecologists (ACOG) released a Committee Opinion supporting over-the-counter (OTC) access to oral contraceptive pills (1). A growing body of evidence indicates that OTC provision of oral contraceptives is safe and effective and that women are interested in obtaining pills this way. With half of all U.S. pregnancies being unintended—a ...

CONTEXT Knowing the extent to which contraceptive nonuse, incorrect or inconsistent use, and method failure account for unintended pregnancies ending in abortion, as well as reasons for nonuse and imperfect use, can help policymakers and family planning providers support effective contraceptive use. METHODS Contraceptive use patterns among a nationally representative sample of 10,683 women re...

Kenya has one of the highest population growth rates in the world. Innovative programs are therefore called for to help curb the fast population growth rate. The Kenya Medical Association started a new program of involving private physicians in the active provision of family planning services. A preliminary analysis shows that the program serves generally young, better educated women of low par...

Severe premenstrual syndrome (PMS) and, more recently, premenstrual dysphoric disorder (PMDD) have been studied extensively over the last 20 years. The defining criteria for diagnosis of the disorders according to the American College of Obstetricians and Gynecologists (ACOG) include at least one moderate to severe mood symptom and one physical symptom for the diagnosis of PMS and by DSM IV cri...

Plasma macrophage colony-stimulating factor (M-CSF) levels were measured by enzyme immunosorbent assay (ELISA) using horse and rabbit polyvalent antibodies raised against human M-CSF purified from urine (hM-CSF). Plasma M-CSF levels in nonpregnant female controls were 364 +/- 69 U/mL (mean +/- SD, n = 20). Pregnancy results in significant elevation of circulating M-CSF levels (541 +/- 164 U/mL,...

For determination of the incidence of renal events in autosomal dominant polycystic kidney disease (ADPKD) all patients who had ADPKD and attended nephrology/urology clinics in Newfoundland in 1981 were identified, and members of 18 families who were at 50% risk for inheriting ADPKD were followed prospectively for 22 yr, including research clinics at 6-yr intervals. Time to hypertension treatme...

Contraception has become critical in managing zoo populations, both to limit production of surplus animals and to promote genetic health. One role of the Contraception Advisory Group, formed in 1989, is to coordinate research to develop new contraceptive methods. Because melengestrol acetate (MGA) implants, which have been used by zoos for almost 20 years, recently have been associated with ute...