To analyze the clinical symptoms and signs in cases of oral submucous fibrosis which has transformed into squamous cell carcinoma, twenty-nine patients with squamous cell carcinoma correlated with oral submucous fibrosis, leukoplakia, lichen planus were taken biopsy for positive diagnosis. The clinical and pathological diagnosis of oral submucous fibrosis depended on clinical and pathological d...

OBJECTIVES/HYPOTHESIS To assess the efficacy of laser therapy for the management of premalignant oral lesions. STUDY DESIGN The study group consisted of seventy consecutive laser-treated patients with oral leukoplakia. The microscopic diagnosis included idiopathic focal keratosis, dysplasias of all grades, and verrucous hyperplasia (proliferative verrucous leukoplakia). Thirty-nine patients h...

The current study was carried out to determine if changes in the oral microbiome were associated with oral leukoplakia. Swabs of oral leukoplakias were taken from 36 patients. Contralateral normal tissue was also swabbed. Swabs from 35 control patients without symptoms of leukoplakia were also taken. DNA was extracted and the V1V2 region of the 16s rRNA gene was sequenced using the Illumina MiS...

In day today practice we see multiple numbers of cases of white lesions in the oral cavity; oral leukoplakia is one of prevalent white lesion.Proliferative verrucousleukoplakia(PVL) is exceptional and aggressive type of oral leukoplakia.A multifocal or diffuse extension makes the lesion inscrutable. In case of proliferative verrucous leukoplakia it is important to give a “clinicopathological” c...

The diagnosis of Darier disease of the oral mucosa was made only after biopsying a leukoplakia-like lesion of the palate.

This article is a systematic review to evaluate the role of LASER in treatment LP and OLP. These two are potentially malignant disorder with high prevalence rate transformation. Many modality been stated for same but has attracted special attention properties it possess. : The aim this research was compare effectiveness (light amplification by stimulated emission radiation) on management leukop...

Background: The disfiguring defects, functional loss and thus the mortality rate in oral squamous cell carcinoma (OSCC) can be significantly reduced by its early diagnosis. Tumour markers are being studied which could aid in screening, diagnosis, study prognosis and monitor the response to treatment. This research was conducted to study the role of Beta 2 microglobulin (B2M), a tumour marker in...

Change in the area of premalignant lesions is an end point in estimating the efficacy of chemopreventive agents. When examiners round measurements of lesion length and width, they introduce variability, which perturbs the relative percent change in lesion area and, consequently, the percent of subjects showing a clinical response. We use simulations to illustrate the resulting bias when the age...