Applications of chiral organocatalysts in reaction types capable forming C-C bonds, such as Michael addition, are one the important research areas recent years. One best examples works organic types, is nitroolefins with ketones presence organocatalysts. In this study, L-proline-based amide derivative was synthesized moderate yield and its structure elucidated by various techniques. As an organ...

A systematic study concerning the immobilisation onto magnetic nanoparticles of three useful classes of chiral organocatalyst which rely on a confluence of weak, easily perturbed van der Waals and hydrogen bonding interactions to promote enantioselective reactions has been undertaken for the first time. The catalysts were evaluated in three different synthetically useful reaction classes: the k...

A simple, highly efficient and green procedure for the condensation of o-phenylenediamines with 1, 2-dicarbonyl compounds in the presence of vitamin C, as an inexpensive organocatalyst, is described. Using this method, variety of quinoxaline derivatives with different electron releasing and electron withdrawing substituents, are produced in high to excellent yields at room temperature in ethano...

An efficient, novel bifunctional C2-symmetric ionic liquid–supported (S)-proline organocatalyst 7 was developed for a one-pot, five-component reaction involving ?-keto esters 8, aryl aldehydes 9, and amines 10, affording highly functionalized tetrahydropyridines 11a–o by simultaneous generation of fives bonds two stereogenic centers with extraordinary diastereo- enantioselectivities (up to >...

Abstract Herein, we present a novel approach for various asymmetric transformations of cyclic enones. The combination readily accessible chiral diamines and sterically demanding flexible phosphoric acids resulted in simple highly tunable catalyst framework. careful optimization the components led to identification particularly powerful multi‐purpose organocatalyst, which was successfully applie...