BACKGROUND Organophosphate poisoning is a major public health problem in South Africa. Individuals get exposed to organophosphate in both the domestic and industrial spheres. METHOD A cross-sectional study was conducted using retrospective, secondary data of organophosphate poisoning cases over a 3-year period, reported at the Tshwane District surveillance office. Data were analysed using Mic...

Organophosphate hydrolases are proficient catalysts of the breakdown of neurotoxic organophosphates and have great potential as both biotherapeutics for treating acute organophosphate toxicity and as bioremediation agents. However, proficient organophosphatases such as serum paraoxonase 1 (PON1) and the organophosphate-hydrolyzing lactonase SsoPox are unable to hydrolyze bulkyorganophosphates w...

BACKGROUND There are different materials and principles used in the construction of bed encasings. Although these covers claim to have antimite properties, they might not be mite proof. OBJECTIVE This study evaluated the effectiveness of mite penetration of these covers by using the Siriraj chamber method. METHODS Thirty-two covers collected from 9 different countries were categorized accor...

Tick vaccines have been available for more than 20 years. They are useful and effective control agents when used properly. However, no new products have emerged since the Bm86-based Gavac vaccine was commercialized. Acaricide resistance is a problem with no abatement in sight and anti-tick vaccines are likely to be relied upon even more in the coming years. As human medicine and plant agricultu...

Southern cattle ticks, Boophilus microplus (Canestrini) (Acari: Ixodidae), collected in Coahuila, Mexico, were determined to be resistant to permethrin. Discriminating concentration (DC) tests at the LC99 and 2X the LC99 of susceptible ticks produced 0 and 0.5% mortality, respectively, for permethrin. However, measured mortalities for coumaphos and amitraz acaricides were within the expected ra...

OBJECTIVES To measure the exposure of a group of farmers to organophosphate pesticide in sheep dip, and to record the incidence of symptoms after exposure. DESIGN A prospective study of the autumn 1992 dipping period. Working methods were assessed by questionnaire. Absorption of organophosphate pesticide was estimated before, immediately after, and six weeks after dipping by measuring plasma ...

The organophosphate pesticides have been used extensively for plant protection; however these chemicals may be toxic to mammals (1,2). Insecticidal action and toxic effect are due to their being potent cholinesterase inhibitors (3,4). Acetylcholine is believed to be the primary transmitter affected by organophosphate insecticides. Although the pesticidal action of organophosphate insecticides h...

BACKGROUND/AIMS Organophosphate poisoning has a high mortality rate. Recently, differences among organophosphorus insecticides in human self-poisoning were reported. This study investigated the prognostic risk factors and the mortality of different organophosphates following acute organophosphate poisoning. METHODS This retrospective study included 68 patients with acute organophosphate poiso...