OBJECTIVES To explore differences in experiences of care reported in the Cancer Patient Experience Survey (CPES) between patients with cancer of unknown primary (CUP) and those with metastatic disease of known primary (non-CUP); to determine insights pertaining to the experiences of care for CUP respondents from free-text comments. DESIGN Two separate, but related, studies, involving secondar...

high temperature, high radiance, low vapor pressure, and lack of precipitation in most months characterize arid ecosystems. under these conditions, tree crops such as pistachio suffer from drought combined with salinity stress. in order to investigation effects of combined salinity and drought stress on function of photosynthetic apparatus, mutica pistachio (pistacia mutica) seedlings were subj...

Background: While the blood–brain barrier (BBB) is often compromised in glioblastoma (GB), perfusion and consequent delivery of drugs are highly heterogeneous. Moreover, accessibility largely impaired margins tumor for infiltrating cells at origin recurrence. In this work, we evaluate value methods to assess hemodynamic changes induced by a hyperosmolar shock core GB model. Methods: Osmotic was...

BACKGROUND Some nonstemmed hip systems have been developed to avoid stress shielding and aseptic loosening, which are major drawbacks of stemmed hip arthroplasty. Without the stem, the cup over the femoral head can be stabilized by anatomic fitness of the cup interior and mechanical fixation of the auxiliary screws. METHODS Using finite-element method, neck-shaped systems with two bone-cup fi...

This paper studies a simple dynamic model of interbank credit relationships. Starting from a given balance sheet structure of a banking system with a realistic distribution of bank sizes, the necessity of establishing interbank credit connections emerges from idiosyncratic liquidity shocks. Banks initially choose potential trading partners randomly, but over time form preferential relationships...

The elastic fiber consists of several components: a central core of alpha-elastin and a microfibrillar sheath containing three components: fibrillin, microfibril-associated glycoprotein, and a 35-kD protein with amine oxidase activity. Elastin is a major component of the elastic fibers of the extracellular matrix (ECM) of the lamina cribrosa, and elastic fibers undergo marked changes in primary...