نتایج جستجو برای: other chemicals
تعداد نتایج: 1791991 فیلتر نتایج به سال:
1. BACKGROUND ln 1969, the International Agency for Research on Cancer (IARC) initiated a programme to evaluate the carcinogenic rik of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of expsures to complex mixures of chemicals (which ocur, for exampie, in sorne ocupations and as a result of human h...
Seizurogenic chemicals include a variety of toxic agents, including chemical warfare agents, toxic industrial chemicals, and natural toxins. Chemical weapons such as sarin and VX, and pesticides such as parathion and carbaryl cause hyperstimulation of cholinergic receptors and an increase in excitatory neurotransmission. Glutamatergic hyperstimulation can occur after exposure to excitatory amin...
The pervasiveness of chemicals in the environment with estrogenic activity and other biological functions recommends the development of new approaches to monitor and study them. Chemicals can be screened for activity in vitro using a panel of human or animal cells that have been transfected with a specific receptor and reporter gene; for example, the estrogen receptor. By using a variety of dif...
As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and co...
Concern about possible adverse effects caused by the inadvertent exposure of humans and wildlife to endocrine-active chemicals, has led some countries to develop an in vivo-in vitro screening program for endocrine effects. In this paper, a previously described estrogen-inducible recombinant yeast strain (Saccharomyces cerevisiae) is used to investigate a number of issues that could potentially ...
Background and aims In the most chemical process industries, workers are exposed to various chemicals and working with these chemicals without considering safety and health considerations can lead to different harmful symptoms. For deciding about control measures and reducing risk to acceptable level , it is necessary to assess the health risk of exposing to harmful chemicals by aid of specif...
Since the 1970s, an increasing number of regulations have expanded the use of brominated and chlorinated flame retardants. Many of these chemicals are now recognized as global contaminants and are associated with adverse health effects in animals and humans, including endocrine and thyroid disruption, immunotoxicity, reproductive toxicity, cancer, and adverse effects on fetal and child developm...
OBJECTIVE This study was conducted to confirm the definition of multiple chemical sensitivity (MCS) in actual life: that multiple symptoms are provoked in multiple organs by exposure to, and ameliorated by avoidance of, multiple chemicals at low levels. We used the Ecological Momentary Assessment to monitor everyday symptoms and the active sampling and passive sampling methods to measure enviro...
The defense industry has previously relied heavily on hazardous chemicals in a variety of manufacturing operations. The Environmental Protection Agency (EPA) identified 17 of these hazardous chemicals under the provisions of the 33/50 program that are to be reduced or eliminated. In line with policy decisions and public expectations, the Pentagon is further committed to this reduction effort fo...
BACKGROUND Xenobiotic chemicals with estrogenic activity (EA), such as bisphenol A (BPA), have been reported to have potential adverse health effects in mammals, including humans, especially in fetal and infant stages. Concerns about safety have caused many manufacturers to use alternatives to polycarbonate (PC) resins to make hard and clear, reusable, plastic products that do not leach BPA. Ho...
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