Multiple Sclerosis is associated with deficient serum 25 hydroxyvitamin D (25 (OH)D) level and cognitive impairment. The aim of this study is to evaluate cognitive performance in MS patients with deficient 25 (OH)D (<25 ng/ml) compared to patients with sufficient levels (>35 ng/ml), then to evaluate the change in cognitive performance after 3 months of vitamin D3 oral replacement. Eighty-eight ...

AIM Overt hypothyroidism is associated with an increased risk for developing cardiovascular disease. We aimed to assess the changes in renal function, serum lipids, vitamin B12, folic acid and homocysteine levels before and after treatment in hypothyroid patients. METHODS The study included 54 patients (F/M=47/7) with overt hypothyroidism. All patients were assessed for demographic characteri...

OBJECTIVE The purpose of the present study was to evaluate the hormonal profile of patients of postmenopausal age during estrogen replacement therapy (ERT) with special reference to the serum levels of biologically active FSH (B-FSH) in a self-adjusted ERT model. DESIGN The hormonal values found have been correlated to climateric symptoms reported by the patients (scored by the Kupperman meno...

Because of the development in parenteral nutrition, the replacement of thyroid hormones in hypothyroid or athyroid patients under intravenous hyperalimentation has become a new problem to be considered. We tried parenteral replacement of the hormones, intravenously or by enema, in three such patients. Two patients, 54 y-o and 64 y-o females, who underwent laryngo-esophago-thyroidectomy for cerv...

Diabetes is the most common cause of CKD (chronic kidney disease). also one important diabetic complication. SGLT2 (sodium glucose co‐transporter‐2) inhibitors are new class medication used to lower high blood level in people with type 2 diabetes. In researches demonstrated a significant and clinically relevant reduction risks albuminuria progression nephropathy, doubling serum creatinine level...

A comparison of the levels of serum epinephrine, norepinephrine and blood pressure was made in 25 patients undergoing aorta-coronary bypass or valve replacement who were anaesthetized with a nitrous oxide-narcotic technique. Serum epinephrine and norepinephrine were measured in arterial samples drawn pre-induction, post-induction, before cardiopulmonary bypass, two and eight minutes after initi...

BACKGROUND This paper aimed to verify the effects of renal replacement therapy on changing the levels of serum creatinine for different veno-arterial and veno-venous configurations in prolonged extracorporeal membrane oxygenation (ECMO) patients. METHODS The subjects were chosen 71 patients who had undergone more than 1,440 minutes (24 hours) of the therapy from among 117 patients who had und...

Background: In preeclampsia, hypoalbuminemia reduces plasma colloid osmotic pressure (PCOP) and favors capillary leakage. Replacement with exogenous albumin is a therapeutic alternative.&#x0D; Objective: to determine the effect of replacement on PCOP in patients severe preeclampsia (SP).&#x0D; Methods: A case-control study was carried out 76 pregnant SP from Intensive Care Unit (ICU). The case ...

The relationship between thyroid function and leptin has been extensively studied; however, the mechanisms underlying the changes in thyroid hormone economy that occur during caloric deprivation remain elusive. Our goal was to evaluate the thyroid function of rats submitted to 40% food restriction after chronic leptin replacement. Caloric restriction for 25 days led to significantly reduced ser...